Niacinamide
48 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
48
Total Reports
5
Deaths Reported
1040.0%
Death Rate
Active Ingredients
Niacinamide
Administration Routes
UnknownOralOphthalmic
Species Affected
Dog 47
Human 1
Most Affected Breeds
Shepherd Dog - German 5
Retriever - Labrador 4
Dachshund (unspecified) 3
Retriever - Golden 3
Pit Bull 2
Schnauzer - Miniature 2
Crossbred Canine/dog 2
Dog (unknown) 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Sheepdog - Shetland 1
Most Reported Reactions
Diarrhoea 7
Lethargy (see also Central nervous system depression in 'Neurological') 6
Vomiting 6
Lack of efficacy - NOS 5
Seizure NOS 5
Anorexia 5
Not eating 4
Elevated alanine aminotransferase (ALT) 4
Other abnormal test result NOS 4
Leucocytosis NOS 4
Lethargy (see also Central nervous system depression in Neurological) 4
Emesis (multiple) 3
Outcome Breakdown
Ongoing
25 (52.1%)
Outcome Unknown
7 (14.6%)
Recovered/Normal
6 (12.5%)
Recovered with Sequela
5 (10.4%)
Died
3 (6.3%)
Euthanized
2 (4.2%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.