Drug profile

The FDA adverse-event record for Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, Usp + Triamcinolone Acetonide, Usp

23 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, Usp + Triamcinolone Acetonide, Usp. Species, reactions, and outcomes follow.

#1661 of 2,679
by report volume (all drugs)
23
adverse-event reports
4.3%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, Usp + Triamcinolone Acetonide, Usp ranks #1638 of 2679 by total reports (23). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1638
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, Usp + Triamcinolone Acetonide, Usp has 23 reports now versus 23 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, Usp + Triamcinolone Acetonide, Usp changes

Signature read: death-coded report count at 1 is the most distinctive stamp on Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, Usp + Triamcinolone Acetonide, Usp's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
23
Total Reports
1
Deaths Reported
4.3%
Death-coded share of reports

Active Ingredients

Neomycin Sulfate, UspNystatin, UspThiostrepton, UspTriamcinolone Acetonide, Usp

Administration Routes

UnknownIntraocularOral

Species Affected

Dog 19
Cat 3
Human 1

Most Affected Breeds

Unknown 5
Retriever - Labrador 4
Terrier - Boston 2
Shepherd Dog - Belgian Malinois 1
Domestic Mediumhair 1
Bulldog - French 1
Poodle (unspecified) 1
Maine Coon 1
Shepherd Dog - German 1
Doberman Pinscher 1

Most Reported Reactions

Loss of hearing 14
Vomiting 2
Loose stool 2
Blood in urine 1
Death 1
Eye irritation 1
Medication error 1
Generalised skin reaction 1
Polydipsia 1
Scleritis 1
Cloudy eye (for Miosis, Mydriasis, Anisocoria, Nystagmus - see 'Neurological') 1
Swollen lymph node 1

Outcome Breakdown

Ongoing
13 (54.2%)
Outcome Unknown
8 (33.3%)
Recovered/Normal
2 (8.3%)
Died
1 (4.2%)

Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, Usp + Triamcinolone Acetonide, Usp: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, Usp + Triamcinolone Acetonide, Usp (#1661 of 2,679 by report volume); death-coded 4.3%. PlainBreed drug row · death-coded report count stamp 1 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →