Drug profile

The FDA adverse-event record for Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide

198 FDA reports name Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#536 of 2,679
by report volume (all drugs)
198
adverse-event reports
2.5%
death-coded share
Dog
most-reported species
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Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide ranks #536 of 2679 by total reports (198) and #952 of 1130 by death-coded share (2.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#536
This drug, reports of 2679
#952
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide has 198 reports now versus 185 in that prior snapshot: 13 more (7.0%).

Report change
+13
Death-coded reports
+1
Death-coded share
+0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide changes

Signature read: Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide's 2.5% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
198
Total Reports
5
Deaths Reported
2.5%
Death-coded share of reports

Active Ingredients

Neomycin Sulfate Equivalent To Neomycin BaseNystatinThiostreptonTriamcinolone Acetonide

Administration Routes

UnknownAuricular (Otic)TopicalOralOtherOphthalmic

Species Affected

Dog 159
Cat 30
Human 6
Horse 1
Unknown 1
Other 1

Most Affected Breeds

Retriever - Labrador 20
Domestic Shorthair 19
Unknown 17
Dog (unknown) 9
Shepherd Dog - German 7
Terrier - Yorkshire 6
Dog (other) 5
Bulldog - French 5
Retriever - Golden 5
Terrier - Bull - Staffordshire 5

Most Reported Reactions

Deafness 52
Loss of hearing 51
Vomiting 20
Lack of efficacy - NOS 17
Medication error NOS 16
Accidental exposure 15
Lethargy (see also Central nervous system depression in Neurological) 14
Diarrhoea 10
Weight loss 6
Licking at application site 6
Not eating 5
Emesis (multiple) 5

Outcome Breakdown

Outcome Unknown
94 (47.7%)
Recovered/Normal
46 (23.4%)
Recovered with Sequela
42 (21.3%)
Ongoing
10 (5.1%)
Euthanized
3 (1.5%)
Died
2 (1.0%)

Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (2.5% here), distinct from the volume row.

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 2.5% Multivitamin Supplement 2.5% Ear Medication (Unknown) 2.5% Hydrogen Peroxide 2.5%

What to do with this drug

  • Compare Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide (#536 of 2,679 by report volume); death-coded 2.5%. PlainBreed drug row · death-coded share stamp 2.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →