Drug profile

The FDA adverse-event record for Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide

160 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide. See the species affected, top reactions, and outcomes below.

160
adverse-event reports
1.3%
death-coded share
Dog
most-reported species
45
Loss of hearing - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
160
Total Reports
2
Deaths Reported
1.3%
Death Rate

Active Ingredients

Neomycin Sulfate Equivalent To Neomycin BaseNystatinThiostreptonTriamcinolone Acetonide

Administration Routes

UnknownAuricular (Otic)TopicalOralOther

Species Affected

Dog 129
Cat 23
Human 5
Horse 1
Unknown 1
Other 1

Most Affected Breeds

Retriever - Labrador 17
Unknown 14
Domestic Shorthair 14
Dog (unknown) 6
Terrier - Yorkshire 5
Dog (other) 5
Bulldog - French 5
Crossbred Canine/dog 5
Bulldog (unspecified) 5
Shepherd Dog - German 5

Most Reported Reactions

Loss of hearing 45
Deafness 40
Vomiting 16
Medication error NOS 13
Lack of efficacy - NOS 11
Lethargy (see also Central nervous system depression in Neurological) 11
Accidental exposure 10
Diarrhoea 7
Temporary deafness 5
Licking at application site 5
Emesis (multiple) 4
Reddening of the skin 4

Outcome Breakdown

Outcome Unknown
76 (47.8%)
Recovered/Normal
41 (25.8%)
Recovered with Sequela
30 (18.9%)
Ongoing
10 (6.3%)
Euthanized
1 (0.6%)
Died
1 (0.6%)

Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide Adverse Event Insights

160 reports name Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide; 2 recorded a death outcome (1.3% of reported events, not a population-level mortality rate). Active ingredients: Neomycin Sulfate Equivalent To Neomycin Base, Nystatin, Thiostrepton, Triamcinolone Acetonide. Administration routes: Unknown, Auricular (Otic), Topical, Oral.

By species: Dog (129 reports), Cat (23 reports), Human (5 reports). By breed: Retriever - Labrador (17), Unknown (14), Domestic Shorthair (14).

Leading clinical signs: Loss of hearing (45), Deafness (40), Vomiting (16), Medication error NOS (13). Outcome, 159 coded reports: Outcome Unknown leads at 47.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.