Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide

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160 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
160
Total Reports
2
Deaths Reported
120.0%
Death Rate

Active Ingredients

Neomycin Sulfate Equivalent To Neomycin BaseNystatinThiostreptonTriamcinolone Acetonide

Administration Routes

UnknownAuricular (Otic)TopicalOralOther

Species Affected

Dog 129
Cat 23
Human 5
Horse 1
Unknown 1
Other 1

Most Affected Breeds

Retriever - Labrador 17
Unknown 14
Domestic Shorthair 14
Dog (unknown) 6
Terrier - Yorkshire 5
Dog (other) 5
Bulldog - French 5
Crossbred Canine/dog 5
Bulldog (unspecified) 5
Shepherd Dog - German 5

Most Reported Reactions

Loss of hearing 45
Deafness 40
Vomiting 16
Medication error NOS 13
Lack of efficacy - NOS 11
Lethargy (see also Central nervous system depression in Neurological) 11
Accidental exposure 10
Diarrhoea 7
Temporary deafness 5
Licking at application site 5
Emesis (multiple) 4
Reddening of the skin 4

Outcome Breakdown

Outcome Unknown
76 (47.8%)
Recovered/Normal
41 (25.8%)
Recovered with Sequela
30 (18.9%)
Ongoing
10 (6.3%)
Euthanized
1 (0.6%)
Died
1 (0.6%)

Data Summary

Metric Value
Total adverse event reports 160
Reports involving death 2
Case-fatality rate (reported events) 120.0%
Distinct species in reports 6
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 4

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 160 adverse event reports referencing Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide, including 2 reports in which the animal died — a 120.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredients on file: Neomycin Sulfate Equivalent To Neomycin Base, Nystatin, Thiostrepton, Triamcinolone Acetonide. Reported administration routes include Unknown, Auricular (Otic), Topical, Oral. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide reports are Dog (129 reports), Cat (23 reports), Human (5 reports), with Dog accounting for the largest share. Within those species, Retriever - Labrador (17), Unknown (14), Domestic Shorthair (14) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide are Loss of hearing (45), Deafness (40), Vomiting (16), Medication error NOS (13). Of the 159 reports with a coded outcome, Outcome Unknown is the leading category at 47.8%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Neomycin Sulfate Equivalent To Neomycin Base + Nystatin + Thiostrepton + Triamcinolone Acetonide.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial