Drug profile

The FDA adverse-event record for Neomycin Polymyxin Dexamethasone

39 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Neomycin Polymyxin Dexamethasone. Species, reactions, and outcomes follow.

#1273 of 2,679
by report volume (all drugs)
39
adverse-event reports
15.4%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Neomycin Polymyxin Dexamethasone ranks #1263 of 2679 by total reports (39). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1263
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Neomycin Polymyxin Dexamethasone has 39 reports now versus 39 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Neomycin Polymyxin Dexamethasone changes

Signature read: death-coded share at 15.4% is the most distinctive stamp on Neomycin Polymyxin Dexamethasone's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
39
Total Reports
6
Deaths Reported
15.4%
Death-coded share of reports

Active Ingredients

Neomycin Polymyxin Dexamethasone

Administration Routes

OphthalmicUnknownTopicalNasalIntraocular

Species Affected

Dog 34
Cat 5

Most Affected Breeds

Retriever - Labrador 5
Domestic Shorthair 4
Terrier (unspecified) 2
Siberian Husky 2
Terrier - Yorkshire 2
Chihuahua 2
Spaniel (unspecified) 2
Pug 2
Crossbred Canine/dog 1
Beagle 1

Most Reported Reactions

Vomiting 10
Lethargy (see also Central nervous system depression in 'Neurological') 8
Elevated serum alkaline phosphatase (SAP) 7
Anorexia 6
Elevated alanine aminotransferase (ALT) 6
Other abnormal test result NOS 6
Death 5
Thrombocytopenia 5
Fever 5
Diarrhoea 4
Panting 4
Lack of efficacy - NOS 4

Outcome Breakdown

Ongoing
25 (62.5%)
Died
5 (12.5%)
Recovered/Normal
5 (12.5%)
Outcome Unknown
3 (7.5%)
Euthanized
2 (5.0%)

Neomycin Polymyxin Dexamethasone Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Neomycin Polymyxin Dexamethasone (#1273 of 2,679 by report volume); death-coded 15.4%. PlainBreed drug row · death-coded share stamp 15.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →