Drug profile

The FDA adverse-event record for Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic

14 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic. See the species affected, top reactions, and outcomes below.

14
adverse-event reports
35.7%
death-coded share
Dog
most-reported species
6
Eye disorder NOS (for Photophobia see neurological) - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
14
Total Reports
5
Deaths Reported
35.7%
Death Rate

Active Ingredients

Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic

Administration Routes

OphthalmicUnknownIntraocular

Species Affected

Dog 14

Most Affected Breeds

Pug 4
Poodle (unspecified) 2
Terrier - West Highland White 2
Crossbred Canine/dog 2
Shepherd Dog - Australian 1
Bullmastiff 1
Retriever - Labrador 1
Lhasa Apso 1

Most Reported Reactions

Eye disorder NOS (for Photophobia see neurological) 6
Corneal ulcer 5
Closed eyelid 4
Eye redness 4
Ocular discharge 4
Head tilt - neurological disorder (see also Head tilt - ear disorder) 4
Depressed ocular reflex 4
Death by euthanasia 4
Vomiting 3
Abnormal Schirmer tear test 3
Small intestine ulcer 3
Gastric ulcer 3

Outcome Breakdown

Outcome Unknown
5 (35.7%)
Euthanized
4 (28.6%)
Ongoing
3 (21.4%)
Died
1 (7.1%)
Recovered/Normal
1 (7.1%)

Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic Adverse Event Insights

14 reports name Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic; 5 recorded a death outcome (35.7% of reported events, not a population-level mortality rate). Active ingredient: Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic. Administration routes: Ophthalmic, Unknown, Intraocular.

By species: Dog (14 reports). By breed: Pug (4), Poodle (unspecified) (2), Terrier - West Highland White (2).

Leading clinical signs: Eye disorder NOS (for Photophobia see neurological) (6), Corneal ulcer (5), Closed eyelid (4), Eye redness (4). Outcome, 14 coded reports: Outcome Unknown leads at 35.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.