Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic

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14 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
14
Total Reports
5
Deaths Reported
3570.0%
Death Rate

Active Ingredients

Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic

Administration Routes

OphthalmicUnknownIntraocular

Species Affected

Dog 14

Most Affected Breeds

Pug 4
Poodle (unspecified) 2
Terrier - West Highland White 2
Crossbred Canine/dog 2
Shepherd Dog - Australian 1
Bullmastiff 1
Retriever - Labrador 1
Lhasa Apso 1

Most Reported Reactions

Eye disorder NOS (for Photophobia see neurological) 6
Corneal ulcer 5
Closed eyelid 4
Eye redness 4
Ocular discharge 4
Head tilt - neurological disorder (see also Head tilt - ear disorder) 4
Depressed ocular reflex 4
Death by euthanasia 4
Vomiting 3
Abnormal Schirmer tear test 3
Small intestine ulcer 3
Gastric ulcer 3

Outcome Breakdown

Outcome Unknown
5 (35.7%)
Euthanized
4 (28.6%)
Ongoing
3 (21.4%)
Died
1 (7.1%)
Recovered/Normal
1 (7.1%)

Data Summary

Metric Value
Total adverse event reports 14
Reports involving death 5
Case-fatality rate (reported events) 3570.0%
Distinct species in reports 1
Distinct breeds in reports 8
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 14 adverse event reports referencing Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic, including 5 reports in which the animal died — a 3570.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic. Reported administration routes include Ophthalmic, Unknown, Intraocular. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic reports are Dog (14 reports), with Dog accounting for the largest share. Within those species, Pug (4), Poodle (unspecified) (2), Terrier - West Highland White (2) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic are Eye disorder NOS (for Photophobia see neurological) (6), Corneal ulcer (5), Closed eyelid (4), Eye redness (4). Of the 14 reports with a coded outcome, Outcome Unknown is the leading category at 35.7%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Neomycin + Polymyxin + Bacitracin + Hydrocortisone Ophthalmic.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial