Drug profile

The FDA adverse-event record for Neomycin, Polymyxin B And Bacitracin Zinc

30 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Neomycin, Polymyxin B And Bacitracin Zinc. Species, reactions, and outcomes follow.

#1454 of 2,679
by report volume (all drugs)
30
adverse-event reports
3.3%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Neomycin, Polymyxin B And Bacitracin Zinc ranks #1440 of 2679 by total reports (30). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1440
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Neomycin, Polymyxin B And Bacitracin Zinc has 30 reports now versus 30 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Neomycin, Polymyxin B And Bacitracin Zinc changes

Signature read: Neomycin, Polymyxin B And Bacitracin Zinc's 3.3% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
30
Total Reports
1
Deaths Reported
3.3%
Death-coded share of reports

Active Ingredients

Neomycin, Polymyxin B And Bacitracin Zinc

Administration Routes

OphthalmicIntraocularUnknownTopicalOral

Species Affected

Dog 28
Cat 2

Most Affected Breeds

Crossbred Canine/dog 3
Retriever - Labrador 3
Boxer (German Boxer) 2
Shih Tzu 2
Pug 2
Bulldog 1
Spaniel - Tibetan 1
Mastiff 1
Spitz - American Eskimo Dog 1
Bichon Frise 1

Most Reported Reactions

Ocular discharge 7
Vomiting 6
Diarrhoea 6
Other abnormal test result NOS 5
Emesis 4
Lack of efficacy - NOS 4
Blepharospasm 4
Corneal ulcer 4
Weight loss 3
Hyperphosphataemia 3
Nasal discharge 3
Schirmer tear test 3

Outcome Breakdown

Outcome Unknown
14 (46.7%)
Recovered/Normal
8 (26.7%)
Ongoing
7 (23.3%)
Euthanized
1 (3.3%)

Neomycin, Polymyxin B And Bacitracin Zinc: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Neomycin, Polymyxin B And Bacitracin Zinc (#1454 of 2,679 by report volume); death-coded 3.3%. PlainBreed drug row · death-coded share stamp 3.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →