Drug profile

The FDA adverse-event record for Neomycin, Polymyxin B And Bacitracin Zinc

29 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Neomycin, Polymyxin B And Bacitracin Zinc. See the species affected, top reactions, and outcomes below.

29
adverse-event reports
3.4%
death-coded share
Dog
most-reported species
7
Ocular discharge - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
29
Total Reports
1
Deaths Reported
3.4%
Death Rate

Active Ingredients

Neomycin, Polymyxin B And Bacitracin Zinc

Administration Routes

OphthalmicIntraocularUnknownTopicalOral

Species Affected

Dog 27
Cat 2

Most Affected Breeds

Retriever - Labrador 3
Boxer (German Boxer) 2
Shih Tzu 2
Crossbred Canine/dog 2
Pug 2
Bulldog 1
Spaniel - Tibetan 1
Mastiff 1
Spitz - American Eskimo Dog 1
Bichon Frise 1

Most Reported Reactions

Ocular discharge 7
Vomiting 6
Diarrhoea 6
Other abnormal test result NOS 5
Emesis 4
Lack of efficacy - NOS 4
Blepharospasm 4
Corneal ulcer 4
Weight loss 3
Hyperphosphataemia 3
Nasal discharge 3
Schirmer tear test 3

Outcome Breakdown

Outcome Unknown
13 (44.8%)
Recovered/Normal
8 (27.6%)
Ongoing
7 (24.1%)
Euthanized
1 (3.4%)

Neomycin, Polymyxin B And Bacitracin Zinc Adverse Event Insights

29 reports name Neomycin, Polymyxin B And Bacitracin Zinc; 1 recorded a death outcome (3.4% of reported events, not a population-level mortality rate). Active ingredient: Neomycin, Polymyxin B And Bacitracin Zinc. Administration routes: Ophthalmic, Intraocular, Unknown, Topical.

By species: Dog (27 reports), Cat (2 reports). By breed: Retriever - Labrador (3), Boxer (German Boxer) (2), Shih Tzu (2).

Leading clinical signs: Ocular discharge (7), Vomiting (6), Diarrhoea (6), Other abnormal test result NOS (5). Outcome, 29 coded reports: Outcome Unknown leads at 44.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.