Drug profile

The FDA adverse-event record for Neomycin + Nystatin + Thiostrepton + Triamcinolone Acetonide

81 FDA reports name Neomycin + Nystatin + Thiostrepton + Triamcinolone Acetonide, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#868 of 2,679
by report volume (all drugs)
81
adverse-event reports
3.7%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Neomycin + Nystatin + Thiostrepton + Triamcinolone Acetonide ranks #866 of 2679 by total reports (81) and #865 of 1130 by death-coded share (3.7%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#866
This drug, reports of 2679
#865
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Neomycin + Nystatin + Thiostrepton + Triamcinolone Acetonide has 81 reports now versus 79 in that prior snapshot: 2 more (2.5%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Neomycin + Nystatin + Thiostrepton + Triamcinolone Acetonide changes

Signature read: Neomycin + Nystatin + Thiostrepton + Triamcinolone Acetonide's 3.7% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
81
Total Reports
3
Deaths Reported
3.7%
Death-coded share of reports

Active Ingredients

NeomycinNystatinThiostreptonTriamcinolone Acetonide

Administration Routes

Auricular (Otic)TopicalUnknownOralOphthalmic

Species Affected

Dog 69
Cat 8
Unknown 4

Most Affected Breeds

Chihuahua 8
Domestic Shorthair 7
Unknown 4
Retriever - Labrador 4
Retriever - Golden 3
Dog (unknown) 3
Shepherd Dog - German 3
Bulldog - French 3
Pug 3
Shih Tzu 3

Most Reported Reactions

Deafness 25
Vomiting 7
Loss of hearing 7
Lethargy (see also Central nervous system depression in Neurological) 7
Lack of efficacy - NOS 6
Diarrhoea 6
Partial deafness 6
Not eating 5
Accidental exposure 5
Ear discharge 5
Polyuria 3
Polydipsia 3

Outcome Breakdown

Recovered with Sequela
25 (32.5%)
Outcome Unknown
25 (32.5%)
Recovered/Normal
21 (27.3%)
Ongoing
3 (3.9%)
Euthanized
3 (3.9%)

Neomycin + Nystatin + Thiostrepton + Triamcinolone Acetonide: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Neomycin + Nystatin + Thiostrepton + Triamcinolone Acetonide, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (3.7% here), distinct from the volume row.

What to do with this drug

  • Compare Neomycin + Nystatin + Thiostrepton + Triamcinolone Acetonide's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Neomycin + Nystatin + Thiostrepton + Triamcinolone Acetonide (#868 of 2,679 by report volume); death-coded 3.7%. PlainBreed drug row · death-coded share stamp 3.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →