Drug profile

The FDA adverse-event record for Multiple Electrolytes Solution

26 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Multiple Electrolytes Solution. Species, reactions, and outcomes follow.

#1561 of 2,679
by report volume (all drugs)
26
adverse-event reports
46.2%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Multiple Electrolytes Solution ranks #1543 of 2679 by total reports (26). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1543
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Multiple Electrolytes Solution has 26 reports now versus 26 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Multiple Electrolytes Solution changes

Signature read: Multiple Electrolytes Solution's 46.2% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
26
Total Reports
12
Deaths Reported
46.2%
Death-coded share of reports

Active Ingredients

Multiple Electrolytes Solution

Administration Routes

IntravenousUnknownSubcutaneousParenteral

Species Affected

Dog 14
Cat 12

Most Affected Breeds

Domestic Shorthair 5
Retriever - Golden 3
Ragdoll 3
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Terrier - Bull - Miniature 2
Mixed (Dog) 1
Domestic Mediumhair 1
Spitz - German Pomeranian 1
Cat (unknown) 1
American Pit Bull Terrier 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in Neurological) 12
Not eating 8
Death by euthanasia 8
Decreased appetite 5
Weight loss 5
Decreased haematocrit 5
Elevated alanine aminotransferase (ALT) 5
Anorexia 5
Monocytosis 5
Elevated gamma-glutamyl transferase (GGT) 5
Death 4
Loose stool 4

Outcome Breakdown

Outcome Unknown
11 (42.3%)
Euthanized
8 (30.8%)
Died
4 (15.4%)
Recovered/Normal
2 (7.7%)
Ongoing
1 (3.8%)

Multiple Electrolytes Solution: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Multiple Electrolytes Solution (#1561 of 2,679 by report volume); death-coded 46.2%. PlainBreed drug row · death-coded share stamp 46.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →