Drug profile

The FDA adverse-event record for Moxidectin, Praziquantel

16 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Moxidectin, Praziquantel. See the species affected, top reactions, and outcomes below.

16
adverse-event reports
18.8%
death-coded share
Horse
most-reported species
3
Trembling - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
16
Total Reports
3
Deaths Reported
18.8%
Death Rate

Active Ingredients

Moxidectin, Praziquantel

Administration Routes

OralUnknownTopical

Species Affected

Horse 9
Unknown 3
Dog 2
Goat 1
Human 1

Most Affected Breeds

Quarter Horse 5
Unknown 4
Tennessee Walking Horse 1
Boer 1
Paint 1
Horse (unknown) 1
Deutsche Dogge, Great Dane 1
Mixed (Horse) 1
Shepherd Dog - Australian 1

Most Reported Reactions

Trembling 3
Abdominal pain 3
Ataxia 2
Anorexia 2
Depression 2
Digestive tract disorder NOS 2
Urticaria 2
Unclassifiable adverse event 2
Accidental exposure 2
Syringe, Abnormal 2
Vials, Leaking 1
Missing Cap 1

Outcome Breakdown

Died
3 (100.0%)

Moxidectin, Praziquantel Adverse Event Insights

16 reports name Moxidectin, Praziquantel; 3 recorded a death outcome (18.8% of reported events, not a population-level mortality rate). Active ingredient: Moxidectin, Praziquantel. Administration routes: Oral, Unknown, Topical.

By species: Horse (9 reports), Unknown (3 reports), Dog (2 reports). By breed: Quarter Horse (5), Unknown (4), Tennessee Walking Horse (1).

Leading clinical signs: Trembling (3), Abdominal pain (3), Ataxia (2), Anorexia (2). Outcome, 3 coded reports: Died leads at 100.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.