Mirtazapine
2,444 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
2,444
Total Reports
424
Deaths Reported
1730.0%
Death Rate
Active Ingredients
Mirtazapine
Administration Routes
UnknownTransdermalOralTopicalIntradermalAuricular (Otic)OphthalmicOtherRespiratory (Inhalation)Cutaneous
Species Affected
Cat 1,593
Unknown 540
Dog 257
Human 50
Other 2
Tiger 1
Fallow 1
Most Affected Breeds
Domestic Shorthair 894
Unknown 596
Cat (unknown) 210
Domestic Longhair 141
Siamese 68
Domestic Mediumhair 60
Maine Coon 37
Retriever - Labrador 35
Ragdoll 26
Persian 22
Most Reported Reactions
Death by euthanasia 276
Lack of efficacy - NOS 256
Appearance, Abnormal 251
Vomiting 246
Anorexia 201
Weight loss 193
Lethargy (see also Central nervous system depression in 'Neurological') 183
Not eating 148
Diarrhoea 141
Death 140
Application site reddening 139
Decreased appetite 136
Outcome Breakdown
Outcome Unknown
631 (33.1%)
Recovered/Normal
496 (26.0%)
Ongoing
348 (18.2%)
Euthanized
277 (14.5%)
Died
149 (7.8%)
Recovered with Sequela
7 (0.4%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.