Milbemycin/Praziquantel
217 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
217
Total Reports
4
Deaths Reported
180.0%
Death Rate
Active Ingredients
Milbemycin/Praziquantel
Administration Routes
OralUnknown
Species Affected
Dog 217
Most Affected Breeds
Retriever - Labrador 41
Crossbred Canine/dog 12
Terrier - Bull - American Pit 12
Retriever - Golden 11
Chihuahua 8
Dog (unknown) 7
Beagle 7
Shepherd Dog - German 7
Great Pyrenees 7
Terrier (unspecified) 6
Most Reported Reactions
Lack of efficacy (endoparasite) - heartworm 103
Vomiting 30
Seizure NOS 26
Lethargy (see also Central nervous system depression in 'Neurological') 17
Ataxia 11
Tremor 10
Diarrhoea 7
Anorexia 7
Shaking 6
Head tremor 6
Behavioural disorder NOS 5
Restlessness 5
Outcome Breakdown
Ongoing
152 (70.0%)
Recovered/Normal
33 (15.2%)
Outcome Unknown
28 (12.9%)
Died
3 (1.4%)
Euthanized
1 (0.5%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.