Milbemycin + Spinosad
42 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
42
Total Reports
6
Deaths Reported
1430.0%
Death Rate
Active Ingredients
MilbemycinSpinosad
Administration Routes
OralUnknownTopical
Species Affected
Dog 42
Most Affected Breeds
Maltese 5
Retriever - Labrador 4
Dog (unknown) 4
Terrier - Yorkshire 3
Retriever - Golden 3
Crossbred Canine/dog 2
Chihuahua 1
Terrier - Boston 1
Terrier - Bull - American Pit 1
Bichon Frise 1
Most Reported Reactions
Vomiting 15
Lack of efficacy - NOS 9
Lethargy (see also Central nervous system depression in 'Neurological') 8
Lack of efficacy (ectoparasite) - flea 6
Seizure NOS 6
Diarrhoea 6
Behavioural disorder NOS 4
Anorexia 4
Death by euthanasia 3
PR-LIVER, LESION(S) 3
Pruritus 2
Bloody diarrhoea 2
Outcome Breakdown
Recovered/Normal
16 (39.0%)
Outcome Unknown
12 (29.3%)
Ongoing
7 (17.1%)
Died
3 (7.3%)
Euthanized
3 (7.3%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.