Milbemycin Oxime,Praziquantel Micronized
137 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
137
Total Reports
3
Deaths Reported
220.0%
Death Rate
Active Ingredients
Milbemycin Oxime,Praziquantel Micronized
Administration Routes
OralUnknownTopical
Species Affected
Dog 136
Unknown 1
Most Affected Breeds
Retriever - Labrador 14
Crossbred Canine/dog 10
Retriever - Golden 10
Shepherd Dog - Australian 8
Shepherd Dog - German 7
Dog (unknown) 7
Beagle 7
Terrier - Bull - American Pit 6
Dachshund (unspecified) 5
Collie - Border 5
Most Reported Reactions
Lack of efficacy (endoparasite) - heartworm 46
Vomiting 19
Lack of efficacy (endoparasite) - hookworm 14
Diarrhoea 14
Lack of efficacy (endoparasite) - tapeworm 12
Lack of efficacy (endoparasite) - roundworm NOS 8
Lethargy (see also Central nervous system depression in Neurological) 7
Elevated alanine aminotransferase (ALT) 6
Collapse NOS (see also Cardio-vascular and Neurological disorders) 5
Not eating 5
Lack of efficacy (bacteria) - Borrelia 4
Seizure NOS 4
Outcome Breakdown
Outcome Unknown
85 (62.5%)
Recovered/Normal
25 (18.4%)
Ongoing
23 (16.9%)
Euthanized
3 (2.2%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.