Milbemycin Oxime, Spinosad

20 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

0.0%

Death Rate

Active Ingredients

Milbemycin Oxime, Spinosad

Administration Routes

OralUnknown

Species Affected

Dog 20

Most Affected Breeds

Retriever - Labrador 6

Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1

Maltese 1

Lhasa Apso 1

Terrier - West Highland White 1

Spaniel - King Charles Cavalier 1

Bichon Frise 1

Terrier - Silky 1

Terrier - Boston 1

Retriever - Golden 1

Most Reported Reactions

Lack of efficacy (endoparasite) - heartworm 7

Lethargy (see also Central nervous system depression in 'Neurological') 3

Other abnormal test result NOS 3

INEFFECTIVE, HEARTWORM LARVAE 2

Seizure NOS 2

Elevated alanine aminotransferase (ALT) 2

Elevated serum alkaline phosphatase (SAP) 2

Lack of efficacy (endoparasite) - hookworm 2

Drug dose administration interval too long 2

Diarrhoea 1

Trembling 1

Panting 1

Outcome Breakdown

Ongoing

9 (45.0%)

Outcome Unknown

7 (35.0%)

Recovered/Normal

4 (20.0%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.