Milbemycin Oxime, Lufenuron, Praziquantel

74 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

140.0%

Death Rate

Active Ingredients

Milbemycin Oxime, Lufenuron, Praziquantel

Administration Routes

OralUnknown

Species Affected

Dog 73

Unknown 1

Most Affected Breeds

Dog (unknown) 30

Retriever - Labrador 8

Shepherd Dog - German 5

Beagle 4

Crossbred Canine/dog 3

Corgi - Welsh Cardigan 2

Collie - Border 2

Boxer (German Boxer) 1

Pit Bull 1

Poodle - Toy 1

Most Reported Reactions

Vomiting 16

INEFFECTIVE, HOOKS 12

Lack of efficacy (endoparasite) - heartworm 9

Diarrhoea 8

Lethargy (see also Central nervous system depression in 'Neurological') 8

Lack of efficacy (flea) 6

Lack of efficacy (heartworm) 6

Seizure NOS 2

Urinary incontinence 2

Elevated alanine aminotransferase (ALT) 2

Loose stool 2

Lack of efficacy (endoparasite) - roundworm NOS 2

Outcome Breakdown

Outcome Unknown

54 (77.1%)

Recovered/Normal

12 (17.1%)

Ongoing

3 (4.3%)

Died

1 (1.4%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.