Midazolam Hydrochloride
544 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
544
Total Reports
156
Deaths Reported
2870.0%
Death Rate
Active Ingredients
Midazolam Hydrochloride
Administration Routes
UnknownIntravenousIntramuscularSubcutaneousOralNasal
Species Affected
Dog 381
Cat 143
Horse 6
Other 3
Other Birds 2
Other Mammals 1
Primate 1
Rat 1
Ferret 1
Guinea Pig 1
Most Affected Breeds
Domestic Shorthair 82
Retriever - Labrador 38
Dog (unknown) 29
Chihuahua 24
Domestic Longhair 19
Terrier - Yorkshire 14
Siberian Husky 13
Boxer (German Boxer) 13
Cat (other) 13
Shepherd Dog - German 12
Most Reported Reactions
Vomiting 102
Seizure NOS 98
Death 90
Lethargy (see also Central nervous system depression in 'Neurological') 81
Death by euthanasia 68
Anorexia 61
Other abnormal test result NOS 45
Cardiac arrest 40
Fever 38
Elevated alanine aminotransferase (ALT) 37
Bradycardia 34
Diarrhoea 32
Outcome Breakdown
Ongoing
203 (36.8%)
Recovered/Normal
172 (31.2%)
Died
89 (16.2%)
Euthanized
68 (12.3%)
Outcome Unknown
19 (3.4%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.