Microchip

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69 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
69
Total Reports
8
Deaths Reported
1160.0%
Death Rate

Active Ingredients

Microchip

Administration Routes

UnknownSubcutaneousOther

Species Affected

Dog 47
Cat 22

Most Affected Breeds

Domestic Shorthair 15
Retriever - Labrador 7
Boxer (German Boxer) 5
Chihuahua 4
Dog (unknown) 3
Domestic Mediumhair 2
Terrier - Jack Russell 2
Bulldog - French 2
Terrier - Bull - American Pit 2
Terrier (unspecified) 2

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 12
Vomiting 10
Fever 6
Diarrhoea 5
Death 5
Anaemia NOS 5
Application site alopecia 5
Injection site swelling 5
Injection site abscess 4
Hyperthermia 4
Neutropenia 4
Other abnormal test result NOS 4

Outcome Breakdown

Ongoing
34 (48.6%)
Recovered/Normal
17 (24.3%)
Outcome Unknown
11 (15.7%)
Died
6 (8.6%)
Euthanized
2 (2.9%)

Data Summary

Metric Value
Total adverse event reports 69
Reports involving death 8
Case-fatality rate (reported events) 1160.0%
Distinct species in reports 2
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Microchip Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 69 adverse event reports referencing Microchip, including 8 reports in which the animal died — a 1160.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Microchip. Reported administration routes include Unknown, Subcutaneous, Other. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Microchip reports are Dog (47 reports), Cat (22 reports), with Dog accounting for the largest share. Within those species, Domestic Shorthair (15), Retriever - Labrador (7), Boxer (German Boxer) (5) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Microchip are Lethargy (see also Central nervous system depression in 'Neurological') (12), Vomiting (10), Fever (6), Diarrhoea (5). Of the 70 reports with a coded outcome, Ongoing is the leading category at 48.6%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Microchip.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial