Drug profile

The FDA adverse-event record for Microchip

75 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Microchip. Species, reactions, and outcomes follow.

#906 of 2,679
by report volume (all drugs)
75
adverse-event reports
10.7%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Microchip ranks #905 of 2679 by total reports (75) and #518 of 1130 by death-coded share (10.7%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#905
This drug, reports of 2679
#518
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Microchip has 75 reports now versus 75 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Microchip changes

Signature read: 75 reports place Microchip in the upper third of FDA AER volume (#906 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
75
Total Reports
8
Deaths Reported
10.7%
Death-coded share of reports

Active Ingredients

Microchip

Administration Routes

UnknownSubcutaneousOther

Species Affected

Dog 52
Cat 23

Most Affected Breeds

Domestic Shorthair 16
Retriever - Labrador 9
Boxer (German Boxer) 5
Chihuahua 4
Dog (unknown) 3
Shepherd Dog - Belgian Malinois 3
Domestic Mediumhair 2
Terrier - Jack Russell 2
Bulldog - French 2
Terrier - Bull - American Pit 2

Most Reported Reactions

Vomiting 13
Lethargy (see also Central nervous system depression in 'Neurological') 12
Other abnormal test result NOS 9
Fever 8
Diarrhoea 7
Not eating 7
Monocytosis 7
Lethargy (see also Central nervous system depression in Neurological) 6
Death 5
Hyperthermia 5
Thrombocytopenia 5
Anaemia NOS 5

Outcome Breakdown

Ongoing
38 (50.0%)
Recovered/Normal
19 (25.0%)
Outcome Unknown
11 (14.5%)
Died
6 (7.9%)
Euthanized
2 (2.6%)

Microchip Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Microchip, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (75 here).

Similar death-coded share

Nearest other drugs by death-coded share (10.7% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Microchip (#906 of 2,679 by report volume); death-coded 10.7%. PlainBreed drug row · report volume stamp 75 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →