Drug profile

The FDA adverse-event record for Microchip

69 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Microchip. See the species affected, top reactions, and outcomes below.

69
adverse-event reports
11.6%
death-coded share
Dog
most-reported species
12
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
69
Total Reports
8
Deaths Reported
11.6%
Death Rate

Active Ingredients

Microchip

Administration Routes

UnknownSubcutaneousOther

Species Affected

Dog 47
Cat 22

Most Affected Breeds

Domestic Shorthair 15
Retriever - Labrador 7
Boxer (German Boxer) 5
Chihuahua 4
Dog (unknown) 3
Domestic Mediumhair 2
Terrier - Jack Russell 2
Bulldog - French 2
Terrier - Bull - American Pit 2
Terrier (unspecified) 2

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 12
Vomiting 10
Fever 6
Diarrhoea 5
Death 5
Anaemia NOS 5
Application site alopecia 5
Injection site swelling 5
Injection site abscess 4
Hyperthermia 4
Neutropenia 4
Other abnormal test result NOS 4

Outcome Breakdown

Ongoing
34 (48.6%)
Recovered/Normal
17 (24.3%)
Outcome Unknown
11 (15.7%)
Died
6 (8.6%)
Euthanized
2 (2.9%)

Microchip Adverse Event Insights

69 reports name Microchip; 8 recorded a death outcome (11.6% of reported events, not a population-level mortality rate). Active ingredient: Microchip. Administration routes: Unknown, Subcutaneous, Other.

By species: Dog (47 reports), Cat (22 reports). By breed: Domestic Shorthair (15), Retriever - Labrador (7), Boxer (German Boxer) (5).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (12), Vomiting (10), Fever (6), Diarrhoea (5). Outcome, 70 coded reports: Ongoing leads at 48.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.