Drug profile

The FDA adverse-event record for Miconazole 2%, Chlorhexidene Gluconate 2%

22 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Miconazole 2%, Chlorhexidene Gluconate 2%. See the species affected, top reactions, and outcomes below.

22
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
6
Application site reddening - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
22
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Miconazole 2%, Chlorhexidene Gluconate 2%

Administration Routes

TopicalUnknown

Species Affected

Dog 20
Cat 2

Most Affected Breeds

Retriever - Labrador 3
American Pit Bull Terrier 3
Bulldog - French 3
Chihuahua 2
Dog (other) 2
Dachshund - Standard Smooth-haired 1
Dachshund - Standard Long-haired 1
Mastiff 1
Boxer (German Boxer) 1
Domestic Shorthair 1

Most Reported Reactions

Application site reddening 6
Reddening of the skin 5
Skin textural change 3
Lack of efficacy - NOS 3
Crust 2
Low platelet count 2
Large platelets 2
Platelet disorder NOS 2
Increased band neutrophilia 2
Lymphocytosis 2
Monocytosis 2
Elevated symmetrical dimethylarginine (SDMA) 2

Outcome Breakdown

Recovered/Normal
12 (54.5%)
Outcome Unknown
10 (45.5%)

Miconazole 2%, Chlorhexidene Gluconate 2% Adverse Event Insights

22 reports name Miconazole 2%, Chlorhexidene Gluconate 2%; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Miconazole 2%, Chlorhexidene Gluconate 2%. Administration routes: Topical, Unknown.

By species: Dog (20 reports), Cat (2 reports). By breed: Retriever - Labrador (3), American Pit Bull Terrier (3), Bulldog - French (3).

Leading clinical signs: Application site reddening (6), Reddening of the skin (5), Skin textural change (3), Lack of efficacy - NOS (3). Outcome, 22 coded reports: Recovered/Normal leads at 54.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.