Mga (Melengestrol Acetate-Progestin)

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11 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
7
Deaths Reported
6360.0%
Death Rate

Active Ingredients

Mga (Melengestrol Acetate-Progestin)

Administration Routes

OralUnknown

Species Affected

Cattle 11

Most Affected Breeds

Cattle (unknown) 5
Aberdeen Angus 2
Cattle (other) 1
Holstein-Friesian also known as Holstein 1
Crossbred Bovine/Cattle 1
Mixed (Cattle) 1

Most Reported Reactions

Death 5
Digestive tract disorder NOS 2
Death by euthanasia 2
Droopy ear 1
Recumbency 1
Abnormal breathing 1
Pain NOS 1
DEATH-TREATMENT FAILURE 1
Respiratory tract infection NOS 1
Foaming at the mouth 1
Pneumonia 1
Decreased appetite 1

Outcome Breakdown

Died
7 (46.7%)
Outcome Unknown
4 (26.7%)
Recovered/Normal
2 (13.3%)
Ongoing
1 (6.7%)
Euthanized
1 (6.7%)

Data Summary

Metric Value
Total adverse event reports 11
Reports involving death 7
Case-fatality rate (reported events) 6360.0%
Distinct species in reports 1
Distinct breeds in reports 6
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Mga (Melengestrol Acetate-Progestin) Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 11 adverse event reports referencing Mga (Melengestrol Acetate-Progestin), including 7 reports in which the animal died — a 6360.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Mga (Melengestrol Acetate-Progestin). Reported administration routes include Oral, Unknown. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Mga (Melengestrol Acetate-Progestin) reports are Cattle (11 reports), with Cattle accounting for the largest share. Within those species, Cattle (unknown) (5), Aberdeen Angus (2), Cattle (other) (1) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Mga (Melengestrol Acetate-Progestin) are Death (5), Digestive tract disorder NOS (2), Death by euthanasia (2), Droopy ear (1). Of the 15 reports with a coded outcome, Died is the leading category at 46.7%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Mga (Melengestrol Acetate-Progestin).

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial