Drug profile

The FDA adverse-event record for Methylprednisolone Acetate Injectable Suspension

19 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Methylprednisolone Acetate Injectable Suspension. See the species affected, top reactions, and outcomes below.

19
adverse-event reports
10.5%
death-coded share
Cat
most-reported species
4
Inappetence - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
19
Total Reports
2
Deaths Reported
10.5%
Death Rate

Active Ingredients

Methylprednisolone Acetate Injectable Suspension

Administration Routes

UnknownSubcutaneousIntramuscular

Species Affected

Cat 18
Dog 1

Most Affected Breeds

Domestic Shorthair 15
Domestic Mediumhair 2
Domestic Longhair 1
Retriever - Labrador 1

Most Reported Reactions

Inappetence 4
Lethargy (see also Central nervous system depression in 'Neurological') 4
Weight loss 3
Other abnormal test result NOS 3
Lack of efficacy - NOS 3
Vomiting 2
Behavioural disorder NOS 2
Hypersalivation 2
Neoplasia NOS 2
Death by euthanasia 2
Pyoderma 2
INEFFECTIVE, ATOPY CONTROL 2

Outcome Breakdown

Outcome Unknown
7 (36.8%)
Recovered/Normal
7 (36.8%)
Ongoing
3 (15.8%)
Euthanized
2 (10.5%)

Methylprednisolone Acetate Injectable Suspension Adverse Event Insights

19 reports name Methylprednisolone Acetate Injectable Suspension; 2 recorded a death outcome (10.5% of reported events, not a population-level mortality rate). Active ingredient: Methylprednisolone Acetate Injectable Suspension. Administration routes: Unknown, Subcutaneous, Intramuscular.

By species: Cat (18 reports), Dog (1 reports). By breed: Domestic Shorthair (15), Domestic Mediumhair (2), Domestic Longhair (1).

Leading clinical signs: Inappetence (4), Lethargy (see also Central nervous system depression in 'Neurological') (4), Weight loss (3), Other abnormal test result NOS (3). Outcome, 19 coded reports: Outcome Unknown leads at 36.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.