Drug profile

The FDA adverse-event record for Melarsomine Dihydrochloride,Glycerin

17 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Melarsomine Dihydrochloride,Glycerin. See the species affected, top reactions, and outcomes below.

17
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
15
Lack of efficacy (endoparasite) - heartworm - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
17
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Melarsomine Dihydrochloride,Glycerin

Administration Routes

UnknownIntramuscularParenteralTopicalVaginal

Species Affected

Dog 17

Most Affected Breeds

Retriever - Labrador 4
Chihuahua 3
Siberian Husky 2
Pit Bull 1
Shepherd Dog - German 1
Mountain Cur 1
Boxer (German Boxer) 1
Poodle - Standard 1
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Collie - Border 1

Most Reported Reactions

Lack of efficacy (endoparasite) - heartworm 15
Diarrhoea 1
Decreased appetite 1
Sleepiness - systemic disorder 1
Cough 1
Sickness 1
Elevated liver enzymes 1
Ocular discharge 1
Lethargy (see also Central nervous system depression in Neurological) 1
Facial swelling (see also Skin) 1
Reddening of the skin 1
Periorbital oedema 1

Outcome Breakdown

Outcome Unknown
14 (82.4%)
Recovered/Normal
3 (17.6%)

Melarsomine Dihydrochloride,Glycerin Adverse Event Insights

17 reports name Melarsomine Dihydrochloride,Glycerin; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Melarsomine Dihydrochloride,Glycerin. Administration routes: Unknown, Intramuscular, Parenteral, Topical.

By species: Dog (17 reports). By breed: Retriever - Labrador (4), Chihuahua (3), Siberian Husky (2).

Leading clinical signs: Lack of efficacy (endoparasite) - heartworm (15), Diarrhoea (1), Decreased appetite (1), Sleepiness - systemic disorder (1). Outcome, 17 coded reports: Outcome Unknown leads at 82.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.