Melarsomine Dihydrochloride Injection
5,095 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
5,095
Total Reports
198
Deaths Reported
390.0%
Death Rate
Active Ingredients
Melarsomine Dihydrochloride Injection
Administration Routes
IntramuscularUnknownSubcutaneousOralOphthalmicParenteralIntravenous
Species Affected
Dog 4,570
Unknown 507
Human 18
Most Affected Breeds
Crossbred Canine/dog 681
Retriever - Labrador 607
Unknown 541
Dog (unknown) 304
Pit Bull 249
Shepherd Dog - German 244
Dog (other) 240
Beagle 207
Chihuahua 174
Boxer (German Boxer) 170
Most Reported Reactions
INEFFECTIVE, HEARTWORM ADULTS 1,260
INEFFECTIVE, HEARTWORM LARVAE 627
Vomiting 595
Injection site swelling 487
Cardiac disorder NOS 458
Lethargy (see also Central nervous system depression in 'Neurological') 442
Pain NOS 330
Vials, Damaged 325
Injection site pain 320
Panting 312
Other abnormal test result NOS 299
Injection site lump 297
Outcome Breakdown
Outcome Unknown
2,939 (64.0%)
Recovered/Normal
613 (13.3%)
Ongoing
518 (11.3%)
Recovered with Sequela
326 (7.1%)
Died
138 (3.0%)
Euthanized
60 (1.3%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.