Drug profile

The FDA adverse-event record for Mannheimia Haemolytica Toxoid

25 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Mannheimia Haemolytica Toxoid. See the species affected, top reactions, and outcomes below.

25
adverse-event reports
92.0%
death-coded share
Cattle
most-reported species
20
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
25
Total Reports
23
Deaths Reported
92.0%
Death Rate

Active Ingredients

Mannheimia Haemolytica Toxoid

Administration Routes

UnknownSubcutaneousParenteralIntramuscular

Species Affected

Cattle 25

Most Affected Breeds

Cattle (other) 14
Cattle (unknown) 5
Crossbred Bovine/Cattle 3
Unknown 1
Charolais 1
Aberdeen Angus 1

Most Reported Reactions

Death 20
Lack of efficacy - NOS 8
Respiratory signs 3
Lack of efficacy (virus) - NOS 3
Foaming at the mouth 2
Death by euthanasia 2
INEFFECTIVE, ANTIBIOTIC 2
Anaphylaxis 2
Lack of efficacy (bacteria) - NOS 2
Lack of efficacy (virus) - bovine viral diarrhoea virus 2
Injection site oedema 1
Stiff gait 1

Outcome Breakdown

Died
22 (59.5%)
Outcome Unknown
8 (21.6%)
Recovered/Normal
3 (8.1%)
Euthanized
2 (5.4%)
Ongoing
2 (5.4%)

Mannheimia Haemolytica Toxoid Adverse Event Insights

25 reports name Mannheimia Haemolytica Toxoid; 23 recorded a death outcome (92.0% of reported events, not a population-level mortality rate). Active ingredient: Mannheimia Haemolytica Toxoid. Administration routes: Unknown, Subcutaneous, Parenteral, Intramuscular.

By species: Cattle (25 reports). By breed: Cattle (other) (14), Cattle (unknown) (5), Crossbred Bovine/Cattle (3).

Leading clinical signs: Death (20), Lack of efficacy - NOS (8), Respiratory signs (3), Lack of efficacy (virus) - NOS (3). Outcome, 37 coded reports: Died leads at 59.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.