Magnesium

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11 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
2
Deaths Reported
1820.0%
Death Rate

Active Ingredients

Magnesium

Administration Routes

UnknownOralIntravenous

Species Affected

Human 4
Horse 2
Dog 2
Cat 1
Alpaca 1
Other 1

Most Affected Breeds

Unknown 5
Horse (unknown) 1
American Shorthair 1
Retriever - Labrador 1
Quarter Horse 1
Alpaca 1
Mastiff (unspecified) 1

Most Reported Reactions

Diarrhoea 3
Accidental exposure 3
Injection site inflammation 2
Seizure NOS 1
Collapse (see also 'Cardio-vascular' and 'Systemic disorders') 1
Sudden death 1
PR-LUNG(S), LESION(S) 1
Dyspnoea 1
Other abnormal test result NOS 1
Adrenal gland disorder NOS 1
Cushings disease - adrenal dependent 1
Spleen and reticulo-endothelial system disorder NOS 1

Outcome Breakdown

Recovered/Normal
4 (36.4%)
Ongoing
3 (27.3%)
Outcome Unknown
2 (18.2%)
Died
1 (9.1%)
Euthanized
1 (9.1%)

Data Summary

Metric Value
Total adverse event reports 11
Reports involving death 2
Case-fatality rate (reported events) 1820.0%
Distinct species in reports 6
Distinct breeds in reports 7
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Magnesium Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 11 adverse event reports referencing Magnesium, including 2 reports in which the animal died — a 1820.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Magnesium. Reported administration routes include Unknown, Oral, Intravenous. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Magnesium reports are Human (4 reports), Horse (2 reports), Dog (2 reports), with Human accounting for the largest share. Within those species, Unknown (5), Horse (unknown) (1), American Shorthair (1) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Magnesium are Diarrhoea (3), Accidental exposure (3), Injection site inflammation (2), Seizure NOS (1). Of the 11 reports with a coded outcome, Recovered/Normal is the leading category at 36.4%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Magnesium.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial