Lotilaner,Moxidectin,Praziquantel,Pyrantel Pamoate
1,067 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,067
Total Reports
28
Deaths Reported
260.0%
Death Rate
Active Ingredients
Lotilaner,Moxidectin,Praziquantel,Pyrantel Pamoate
Administration Routes
OralUnknownTopical
Species Affected
Dog 962
Unknown 104
Cat 1
Most Affected Breeds
Unknown 104
Retriever - Labrador 95
Retriever - Golden 84
Dog (unknown) 76
Shepherd Dog - Australian 52
Shih Tzu 40
Chihuahua 38
Crossbred Canine/dog 37
Shepherd Dog - German 36
Pit Bull 27
Most Reported Reactions
Vomiting 296
Diarrhoea 236
Lethargy (see also Central nervous system depression in Neurological) 118
UNPALATABLE 112
Behavioural disorder NOS 61
Emesis (multiple) 53
Lack of efficacy (endoparasite) - hookworm 49
Not eating 43
Other abnormal test result NOS 43
Lack of efficacy (ectoparasite) - flea 43
Seizure NOS 38
Product defect, product difficult to use/handle (see also 'Drug device difficult to use/handle') 36
Outcome Breakdown
Recovered/Normal
394 (40.9%)
Outcome Unknown
331 (34.3%)
Ongoing
211 (21.9%)
Died
20 (2.1%)
Euthanized
8 (0.8%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.