Drug profile

The FDA adverse-event record for Lotilaner,Moxidectin,Praziquantel,Pyrantel

14 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Lotilaner,Moxidectin,Praziquantel,Pyrantel. See the species affected, top reactions, and outcomes below.

14
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
3
Diarrhoea - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
14
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Lotilaner,Moxidectin,Praziquantel,Pyrantel

Administration Routes

Oral

Species Affected

Dog 14

Most Affected Breeds

Dog (other) 14

Most Reported Reactions

Diarrhoea 3
Ear discharge 2
Weight loss 2
Ear infection NOS 2
Skin irritation 2
Reddening of the skin 2
Chewing - pruritus (see also 'Oral cavity disorders') 2
Skin ulcer 2
Pancreatitis 1
Elevated gamma-glutamyl transferase (GGT) 1
Elevated total bilirubin 1
Leucocytosis NOS 1

Outcome Breakdown

Recovered/Normal
7 (50.0%)
Ongoing
5 (35.7%)
Outcome Unknown
2 (14.3%)

Lotilaner,Moxidectin,Praziquantel,Pyrantel Adverse Event Insights

14 reports name Lotilaner,Moxidectin,Praziquantel,Pyrantel; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Lotilaner,Moxidectin,Praziquantel,Pyrantel. Administration route: Oral.

By species: Dog (14 reports). By breed: Dog (other) (14).

Leading clinical signs: Diarrhoea (3), Ear discharge (2), Weight loss (2), Ear infection NOS (2). Outcome, 14 coded reports: Recovered/Normal leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.