Leptospirosis Vaccine
450 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
450
Total Reports
55
Deaths Reported
1220.0%
Death Rate
Active Ingredients
Leptospirosis Vaccine
Administration Routes
UnknownSubcutaneousParenteralOtherOral
Species Affected
Dog 450
Most Affected Breeds
Retriever - Labrador 55
Retriever - Golden 28
Shepherd Dog - German 26
Shepherd Dog - Australian 23
Chihuahua 20
Crossbred Canine/dog 18
Terrier - Bull - American Pit 15
Shih Tzu 13
Terrier - Yorkshire 13
Boxer (German Boxer) 10
Most Reported Reactions
Vomiting 139
Lethargy (see also Central nervous system depression in Neurological) 72
Diarrhoea 62
Other abnormal test result NOS 52
Lethargy (see also Central nervous system depression in 'Neurological') 49
Not eating 45
Elevated alanine aminotransferase (ALT) 40
Emesis (multiple) 31
Anorexia 30
Death by euthanasia 28
Behavioural disorder NOS 27
Anaphylaxis 26
Outcome Breakdown
Ongoing
159 (35.3%)
Recovered/Normal
134 (29.8%)
Outcome Unknown
98 (21.8%)
Euthanized
29 (6.4%)
Died
26 (5.8%)
Recovered with Sequela
4 (0.9%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.