Drug profile

The FDA adverse-event record for Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8

Name: Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8 - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

11 FDA reports name Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#2473 of 2,679
by report volume (all drugs): 11
adverse-event reports: 27.3%
death-coded share: Dog
most-reported species

Compiled by PlainBreed

Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8 ranks #2412 of 2679 by total reports (11). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1): 97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1): #2412
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8 has 11 reports now versus 11 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8 changes

Signature read: 11 reports place Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8 in the lower third of FDA AER volume (#2473 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

27.3%

Death-coded share of reports

Active Ingredients

Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8

Administration Routes

Subcutaneous

Species Affected

Dog 11

Most Affected Breeds

Retriever - Labrador 3

Chihuahua 1

Dachshund - Miniature 1

Terrier - Boston 1

Terrier - Yorkshire 1

Terrier - Rat 1

Dachshund (unspecified) 1

Poodle - Miniature 1

Schnauzer - Miniature 1

Most Reported Reactions

Emesis 3

Vomiting 2

Seizure NOS 2

Death 2

Cough 2

Anaphylaxis 2

Swollen eye 1

Hives (see also 'Skin') 1

Less social 1

Anorexia 1

Ataxia 1

Disorientation 1

Outcome Breakdown

Ongoing

4 (36.4%)

Recovered/Normal

3 (27.3%)

Died

2 (18.2%)

Outcome Unknown

1 (9.1%)

Euthanized

1 (9.1%)

Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8 (#2473 of 2,679 by report volume); death-coded 27.3%. PlainBreed drug row · report volume stamp 11 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →