Drug profile

The FDA adverse-event record for Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8

11 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8. See the species affected, top reactions, and outcomes below.

11
adverse-event reports
27.3%
death-coded share
Dog
most-reported species
3
Emesis - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
3
Deaths Reported
27.3%
Death Rate

Active Ingredients

Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8

Administration Routes

Subcutaneous

Species Affected

Dog 11

Most Affected Breeds

Retriever - Labrador 3
Chihuahua 1
Terrier - Yorkshire 1
Terrier - Rat 1
Terrier - Boston 1
Dachshund - Miniature 1
Poodle - Miniature 1
Dachshund (unspecified) 1
Schnauzer - Miniature 1

Most Reported Reactions

Emesis 3
Seizure NOS 2
Death 2
Vomiting 2
Cough 2
Anaphylaxis 2
Swollen eye 1
Hives (see also 'Skin') 1
Ataxia 1
Disorientation 1
Blindness 1
Death by euthanasia 1

Outcome Breakdown

Ongoing
4 (36.4%)
Recovered/Normal
3 (27.3%)
Died
2 (18.2%)
Euthanized
1 (9.1%)
Outcome Unknown
1 (9.1%)

Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8 Adverse Event Insights

11 reports name Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8; 3 recorded a death outcome (27.3% of reported events, not a population-level mortality rate). Active ingredient: Leptospira Canicola L-15 Strain C-51;Leptospira Icterohaemorrhagiae, 10010, 10-8. Administration route: Subcutaneous.

By species: Dog (11 reports). By breed: Retriever - Labrador (3), Chihuahua (1), Terrier - Yorkshire (1).

Leading clinical signs: Emesis (3), Seizure NOS (2), Death (2), Vomiting (2). Outcome, 11 coded reports: Ongoing leads at 36.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.