Leflunomide

16 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

3120.0%

Death Rate

Active Ingredients

Leflunomide

Administration Routes

OralUnknown

Species Affected

Dog 15

Human 1

Most Affected Breeds

Crossbred Canine/dog 2

Chihuahua 1

Shepherd Dog - Anatolian 1

Shih Tzu 1

Pug 1

Spaniel - Springer English 1

Shepherd Dog - Australian 1

Catahoula Leopard Dog 1

Cattle Dog (unspecified) 1

Terrier - Jack Russell 1

Most Reported Reactions

Vomiting 6

Anaemia NOS 5

Lethargy (see also Central nervous system depression in 'Neurological') 5

Anorexia 4

Diarrhoea 4

Death by euthanasia 3

Thrombocytopenia 3

Leucocytosis NOS 3

Weight loss 3

Splenomegaly 2

Fever 2

Pancreatitis 2

Outcome Breakdown

Recovered/Normal

5 (31.3%)

Ongoing

4 (25.0%)

Died

3 (18.8%)

Euthanized

2 (12.5%)

Outcome Unknown

2 (12.5%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.