Drug profile

The FDA adverse-event record for Latanoprost

38 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Latanoprost. See the species affected, top reactions, and outcomes below.

38
adverse-event reports
10.5%
death-coded share
Dog
most-reported species
6
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
38
Total Reports
4
Deaths Reported
10.5%
Death Rate

Active Ingredients

Latanoprost

Administration Routes

OphthalmicUnknownOtherTopicalIntraocular

Species Affected

Dog 32
Cat 3
Unknown 2
Human 1

Most Affected Breeds

Shih Tzu 6
Unknown 3
Crossbred Canine/dog 2
Pug 2
Siberian Husky 2
Maltese 2
Chihuahua 2
Domestic Mediumhair 2
Spaniel - Cocker English 1
Hound - Basset 1

Most Reported Reactions

Vomiting 6
Lack of efficacy - NOS 6
Eye disorder NOS (for photophobia see 'neurological') 5
Lethargy (see also Central nervous system depression in 'Neurological') 5
Decreased appetite 4
Cough 3
Neutrophilia 3
Other abnormal test result NOS 3
Abnormal radiograph finding 3
Elevated serum alkaline phosphatase (SAP) 3
Not eating 3
Gagging 2

Outcome Breakdown

Recovered/Normal
14 (38.9%)
Ongoing
9 (25.0%)
Outcome Unknown
6 (16.7%)
Recovered with Sequela
3 (8.3%)
Died
2 (5.6%)
Euthanized
2 (5.6%)

Latanoprost Adverse Event Insights

38 reports name Latanoprost; 4 recorded a death outcome (10.5% of reported events, not a population-level mortality rate). Active ingredient: Latanoprost. Administration routes: Ophthalmic, Unknown, Other, Topical.

By species: Dog (32 reports), Cat (3 reports), Unknown (2 reports). By breed: Shih Tzu (6), Unknown (3), Crossbred Canine/dog (2).

Leading clinical signs: Vomiting (6), Lack of efficacy - NOS (6), Eye disorder NOS (for photophobia see 'neurological') (5), Lethargy (see also Central nervous system depression in 'Neurological') (5). Outcome, 36 coded reports: Recovered/Normal leads at 38.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.