Drug profile

The FDA adverse-event record for K99/Cor*2/Rota*2/Clos Per C,D

17 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference K99/Cor*2/Rota*2/Clos Per C,D. See the species affected, top reactions, and outcomes below.

17
adverse-event reports
58.8%
death-coded share
Cattle
most-reported species
9
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
17
Total Reports
10
Deaths Reported
58.8%
Death Rate

Active Ingredients

K99/Cor*2/Rota*2/Clos Per C,D

Administration Routes

SubcutaneousUnknown

Species Affected

Cattle 17

Most Affected Breeds

Holstein-Friesian also known as Holstein 5
Cattle (other) 5
Aberdeen Angus 4
Crossbred Bovine/Cattle 2
Shorthorn (unspecified) 1

Most Reported Reactions

Death 9
Abortion 5
Anaphylaxis 2
Stiffness limb 2
Premature birth 2
Lateral recumbency 2
Lack of efficacy (bacteria) - NOS 2
Laboured breathing 2
Mastitis NOS 2
Foam in the mouth 1
Foam in the nose 1
Respiratory distress 1

Outcome Breakdown

Died
10 (34.5%)
Outcome Unknown
8 (27.6%)
Recovered/Normal
7 (24.1%)
Ongoing
4 (13.8%)

K99/Cor*2/Rota*2/Clos Per C,D Adverse Event Insights

17 reports name K99/Cor*2/Rota*2/Clos Per C,D; 10 recorded a death outcome (58.8% of reported events, not a population-level mortality rate). Active ingredient: K99/Cor*2/Rota*2/Clos Per C,D. Administration routes: Subcutaneous, Unknown.

By species: Cattle (17 reports). By breed: Holstein-Friesian also known as Holstein (5), Cattle (other) (5), Aberdeen Angus (4).

Leading clinical signs: Death (9), Abortion (5), Anaphylaxis (2), Stiffness limb (2). Outcome, 29 coded reports: Died leads at 34.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.