K99/Cor*2/Rota*2/Clos Per C,D

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17 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
17
Total Reports
10
Deaths Reported
5880.0%
Death Rate

Active Ingredients

K99/Cor*2/Rota*2/Clos Per C,D

Administration Routes

SubcutaneousUnknown

Species Affected

Cattle 17

Most Affected Breeds

Holstein-Friesian also known as Holstein 5
Cattle (other) 5
Aberdeen Angus 4
Crossbred Bovine/Cattle 2
Shorthorn (unspecified) 1

Most Reported Reactions

Death 9
Abortion 5
Anaphylaxis 2
Stiffness limb 2
Premature birth 2
Lateral recumbency 2
Lack of efficacy (bacteria) - NOS 2
Laboured breathing 2
Mastitis NOS 2
Foam in the mouth 1
Foam in the nose 1
Respiratory distress 1

Outcome Breakdown

Died
10 (34.5%)
Outcome Unknown
8 (27.6%)
Recovered/Normal
7 (24.1%)
Ongoing
4 (13.8%)

Data Summary

Metric Value
Total adverse event reports 17
Reports involving death 10
Case-fatality rate (reported events) 5880.0%
Distinct species in reports 1
Distinct breeds in reports 5
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

K99/Cor*2/Rota*2/Clos Per C,D Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 17 adverse event reports referencing K99/Cor*2/Rota*2/Clos Per C,D, including 10 reports in which the animal died — a 5880.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: K99/Cor*2/Rota*2/Clos Per C,D. Reported administration routes include Subcutaneous, Unknown. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in K99/Cor*2/Rota*2/Clos Per C,D reports are Cattle (17 reports), with Cattle accounting for the largest share. Within those species, Holstein-Friesian also known as Holstein (5), Cattle (other) (5), Aberdeen Angus (4) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with K99/Cor*2/Rota*2/Clos Per C,D are Death (9), Abortion (5), Anaphylaxis (2), Stiffness limb (2). Of the 29 reports with a coded outcome, Died is the leading category at 34.5%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on K99/Cor*2/Rota*2/Clos Per C,D.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial