Drug profile

The FDA adverse-event record for Joint Formula (Unknown)

217 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Joint Formula (Unknown). See the species affected, top reactions, and outcomes below.

217
adverse-event reports
3.2%
death-coded share
Dog
most-reported species
34
Emesis - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
217
Total Reports
7
Deaths Reported
3.2%
Death Rate

Active Ingredients

Joint Formula (Unknown)

Administration Routes

OralUnknownParenteral

Species Affected

Dog 209
Cat 5
Human 2
Unknown 1

Most Affected Breeds

Retriever - Labrador 34
Shepherd Dog - German 15
Retriever - Golden 11
Crossbred Canine/dog 9
Pit Bull 9
Terrier - Yorkshire 8
Bulldog 7
Collie (unspecified) 7
Chihuahua 6
Boxer (German Boxer) 6

Most Reported Reactions

Emesis 34
Vomiting 33
Lethargy (see also Central nervous system depression in 'Neurological') 21
Diarrhoea 19
Lack of efficacy - NOS 19
Not eating 16
Behavioural disorder NOS 13
Lack of efficacy (endoparasite) - heartworm 12
Lack of efficacy (ectoparasite) - flea 11
Other abnormal test result NOS 10
Decreased appetite 8
Panting 8

Outcome Breakdown

Recovered/Normal
85 (39.4%)
Outcome Unknown
80 (37.0%)
Ongoing
36 (16.7%)
Recovered with Sequela
8 (3.7%)
Euthanized
5 (2.3%)
Died
2 (0.9%)

Joint Formula (Unknown) Adverse Event Insights

217 reports name Joint Formula (Unknown); 7 recorded a death outcome (3.2% of reported events, not a population-level mortality rate). Active ingredient: Joint Formula (Unknown). Administration routes: Oral, Unknown, Parenteral.

By species: Dog (209 reports), Cat (5 reports), Human (2 reports). By breed: Retriever - Labrador (34), Shepherd Dog - German (15), Retriever - Golden (11).

Leading clinical signs: Emesis (34), Vomiting (33), Lethargy (see also Central nervous system depression in 'Neurological') (21), Diarrhoea (19). Outcome, 216 coded reports: Recovered/Normal leads at 39.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.