Drug profile

The FDA adverse-event record for Ivermectin/Praziquantel Paste

52 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Ivermectin/Praziquantel Paste. See the species affected, top reactions, and outcomes below.

52
adverse-event reports
0.0%
death-coded share
Horse
most-reported species
15
Application site swelling - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
52
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Ivermectin/Praziquantel Paste

Administration Routes

OralTopical

Species Affected

Horse 45
Dog 5
Human 1
Donkey 1

Most Affected Breeds

Quarter Horse 13
Horse (unknown) 7
Thoroughbred 7
Arab 5
Appaloosa 4
Miniature 2
Shetland Pony 2
Shepherd Dog - German 1
Trakehner 1
Standardbred (unspecified) 1

Most Reported Reactions

Application site swelling 15
Lip oedema (see also 'Skin') 11
Swollen mouth 10
Application site oedema 10
Stomatitis 4
Lethargy (see also Central nervous system depression in 'Neurological') 4
Tongue oedema 4
Digestive tract disorder NOS 4
Ataxia 3
Urticaria 3
Facial swelling (see also 'Skin') 3
Drooling 3

Outcome Breakdown

Outcome Unknown
30 (55.6%)
Recovered/Normal
17 (31.5%)
Ongoing
7 (13.0%)

Ivermectin/Praziquantel Paste Adverse Event Insights

52 reports name Ivermectin/Praziquantel Paste; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Ivermectin/Praziquantel Paste. Administration routes: Oral, Topical.

By species: Horse (45 reports), Dog (5 reports), Human (1 reports). By breed: Quarter Horse (13), Horse (unknown) (7), Thoroughbred (7).

Leading clinical signs: Application site swelling (15), Lip oedema (see also 'Skin') (11), Swollen mouth (10), Application site oedema (10). Outcome, 54 coded reports: Outcome Unknown leads at 55.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.