Drug profile

The FDA adverse-event record for Ivermectin/Praziquantel Paste

52 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Ivermectin/Praziquantel Paste. Species, reactions, and outcomes follow.

#1095 of 2,679
by report volume (all drugs)
52
adverse-event reports
0.0%
death-coded share
Horse
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Ivermectin/Praziquantel Paste ranks #1088 of 2679 by total reports (52) and #1101 of 1130 by death-coded share (0.0%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1088
This drug, reports of 2679
#1101
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ivermectin/Praziquantel Paste has 52 reports now versus 52 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ivermectin/Praziquantel Paste changes

Signature read: Ivermectin/Praziquantel Paste's 0.0% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
52
Total Reports
0
Deaths Reported
0.0%
Death-coded share of reports

Active Ingredients

Ivermectin/Praziquantel Paste

Administration Routes

OralTopical

Species Affected

Horse 45
Dog 5
Human 1
Donkey 1

Most Affected Breeds

Quarter Horse 13
Thoroughbred 7
Horse (unknown) 7
Arab 5
Appaloosa 4
Shetland Pony 2
Miniature 2
Trakehner 1
Shepherd Dog - German 1
Standardbred (unspecified) 1

Most Reported Reactions

Application site swelling 15
Lip oedema (see also 'Skin') 11
Application site oedema 10
Swollen mouth 10
Digestive tract disorder NOS 4
Lethargy (see also Central nervous system depression in 'Neurological') 4
Tongue oedema 4
Stomatitis 4
Drooling 3
Ataxia 3
Facial swelling (see also 'Skin') 3
Urticaria 3

Outcome Breakdown

Outcome Unknown
30 (55.6%)
Recovered/Normal
17 (31.5%)
Ongoing
7 (13.0%)

Ivermectin/Praziquantel Paste: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Ivermectin/Praziquantel Paste, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Ivermectin/Praziquantel Paste's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ivermectin/Praziquantel Paste (#1095 of 2,679 by report volume); death-coded 0.0%. PlainBreed drug row · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →