Ivermectin 272Mcg, Pyrantel 227Mg
1,038 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,038
Total Reports
23
Deaths Reported
220.0%
Death Rate
Active Ingredients
Ivermectin 272Mcg, Pyrantel 227Mg
Administration Routes
OralUnknown
Species Affected
Dog 988
Unknown 47
Human 2
Cat 1
Most Affected Breeds
Retriever - Labrador 294
Shepherd Dog - German 99
Retriever - Golden 69
Crossbred Canine/dog 61
Unknown 49
Dog (unknown) 47
Boxer (German Boxer) 36
American Pit Bull Terrier 34
Rottweiler 33
Siberian Husky 18
Most Reported Reactions
INEFFECTIVE, HEARTWORM LARVAE 477
Lack of efficacy - NOS 200
Vomiting 142
Lack of efficacy (endoparasite) - hookworm 133
INEFFECTIVE, ASCARIDS NOS 108
Diarrhoea 75
Drug dose administration interval too long 60
Lethargy (see also Central nervous system depression in 'Neurological') 60
Drug dose omission 46
Underfilling, Package 27
Overdose 25
Uncoded sign 23
Outcome Breakdown
Outcome Unknown
637 (64.3%)
Recovered/Normal
260 (26.2%)
Recovered with Sequela
36 (3.6%)
Ongoing
35 (3.5%)
Died
15 (1.5%)
Euthanized
8 (0.8%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.