Drug profile

The FDA adverse-event record for Ivermectin 1.87% Paste

92 FDA reports name Ivermectin 1.87% Paste, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#814 of 2,679
by report volume (all drugs)
92
adverse-event reports
1.1%
death-coded share
Unknown
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Ivermectin 1.87% Paste ranks #814 of 2679 by total reports (92) and #1062 of 1130 by death-coded share (1.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#814
This drug, reports of 2679
#1062
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ivermectin 1.87% Paste has 92 reports now versus 92 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ivermectin 1.87% Paste changes

Signature read: Ivermectin 1.87% Paste's 1.1% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
92
Total Reports
1
Deaths Reported
1.1%
Death-coded share of reports

Active Ingredients

Ivermectin 1.87% Paste

Administration Routes

OralUnknownOtherParenteral

Species Affected

Unknown 35
Dog 25
Horse 25
Human 4
Cat 3

Most Affected Breeds

Unknown 39
Quarter Horse 8
Dog (unknown) 7
Horse (unknown) 5
Shepherd Dog - Australian 4
Thoroughbred 4
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Standardbred (unspecified) 2
Pit Bull 2
Beagle 2

Most Reported Reactions

Ataxia 23
Uncoded sign 19
Mydriasis 10
Locking Mechanism Abnormal 8
Blindness 7
Containers, Damaged 6
Other abnormal test result NOS 6
Labeled drug-species interaction 6
Difficulty of Use 6
Behavioural disorder NOS 5
Lethargy (see also Central nervous system depression in 'Neurological') 5
Accidental exposure 5

Outcome Breakdown

Outcome Unknown
46 (80.7%)
Recovered/Normal
9 (15.8%)
Ongoing
1 (1.8%)
Died
1 (1.8%)

Ivermectin 1.87% Paste: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Ivermectin 1.87% Paste, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Ivermectin 1.87% Paste's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ivermectin 1.87% Paste (#814 of 2,679 by report volume); death-coded 1.1%. PlainBreed drug row · death-coded share stamp 1.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →