Ivermectin 136Mcg, Pyrantel Pamoate 114Mg, Praziquantel 114Mg
950 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
950
Total Reports
13
Deaths Reported
140.0%
Death Rate
Active Ingredients
Ivermectin 136Mcg, Pyrantel Pamoate 114Mg, Praziquantel 114Mg
Administration Routes
OralUnknown
Species Affected
Dog 917
Unknown 30
Cat 2
Human 1
Most Affected Breeds
Crossbred Canine/dog 134
Beagle 91
Retriever - Labrador 73
Collie - Border 34
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 31
Spaniel - Cocker American 31
Dog (unknown) 31
Unknown 31
Mixed (Dog) 28
Shepherd Dog - German 27
Most Reported Reactions
Vomiting 327
INEFFECTIVE, HEARTWORM LARVAE 243
Lack of efficacy - NOS 174
Lack of efficacy (endoparasite) - hookworm 122
Diarrhoea 102
Lethargy (see also Central nervous system depression in 'Neurological') 83
INEFFECTIVE, ASCARIDS NOS 75
Lack of efficacy (endoparasite) - tapeworm 40
Drug dose administration interval too long 36
Overdose 29
Underdose 21
Underfilling, Package 20
Outcome Breakdown
Outcome Unknown
494 (53.6%)
Recovered/Normal
389 (42.2%)
Ongoing
15 (1.6%)
Recovered with Sequela
10 (1.1%)
Died
8 (0.9%)
Euthanized
5 (0.5%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.