Ivermectin 136Mcg, Pyrantel 114Mg
450 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
450
Total Reports
6
Deaths Reported
130.0%
Death Rate
Active Ingredients
Ivermectin 136Mcg, Pyrantel 114Mg
Administration Routes
OralUnknown
Species Affected
Dog 419
Unknown 29
Human 1
Cat 1
Most Affected Breeds
Crossbred Canine/dog 48
Retriever - Labrador 47
Beagle 45
Unknown 30
Shepherd Dog - German 20
Spaniel - Cocker American 17
Collie - Border 15
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 13
Sheepdog - Shetland 11
Dog (unknown) 11
Most Reported Reactions
INEFFECTIVE, HEARTWORM LARVAE 191
Vomiting 82
Lack of efficacy (endoparasite) - hookworm 62
Lack of efficacy - NOS 59
Diarrhoea 36
INEFFECTIVE, ASCARIDS NOS 35
Drug dose administration interval too long 27
Lethargy (see also Central nervous system depression in 'Neurological') 25
Underfilling, Package 18
Underdose 18
Drug dose omission 16
Uncoded sign 15
Outcome Breakdown
Outcome Unknown
252 (59.9%)
Recovered/Normal
133 (31.6%)
Recovered with Sequela
19 (4.5%)
Ongoing
11 (2.6%)
Died
6 (1.4%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.