Drug profile

The FDA adverse-event record for Iodine

16 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Iodine. See the species affected, top reactions, and outcomes below.

16
adverse-event reports
18.8%
death-coded share
Dog
most-reported species
3
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
16
Total Reports
3
Deaths Reported
18.8%
Death Rate

Active Ingredients

Iodine

Administration Routes

TopicalUnknownOralAuricular (Otic)Subcutaneous

Species Affected

Dog 8
Cat 5
Turkey 2
Cattle 1

Most Affected Breeds

Domestic Shorthair 2
Retriever - Labrador 2
Turkey (unknown) 2
Dog (other) 1
Retriever - Golden 1
Pekingese 1
Spaniel - Cocker American 1
Chihuahua 1
Cattle (unknown) 1
Terrier - Cairn 1

Most Reported Reactions

Vomiting 3
Death 3
Lack of efficacy (ectoparasite) - flea 2
Ataxia 2
Recumbency 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Behavioural disorder NOS 2
Pyoderma 1
Other abnormal test result NOS 1
Anaemia NOS 1
Emesis 1
Odor, Abnormal 1

Outcome Breakdown

Outcome Unknown
10 (52.6%)
Ongoing
3 (15.8%)
Died
3 (15.8%)
Recovered/Normal
2 (10.5%)
Euthanized
1 (5.3%)

Iodine Adverse Event Insights

16 reports name Iodine; 3 recorded a death outcome (18.8% of reported events, not a population-level mortality rate). Active ingredient: Iodine. Administration routes: Topical, Unknown, Oral, Auricular (Otic).

By species: Dog (8 reports), Cat (5 reports), Turkey (2 reports). By breed: Domestic Shorthair (2), Retriever - Labrador (2), Turkey (unknown) (2).

Leading clinical signs: Vomiting (3), Death (3), Lack of efficacy (ectoparasite) - flea (2), Ataxia (2). Outcome, 19 coded reports: Outcome Unknown leads at 52.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.