Drug profile

The FDA adverse-event record for Intravenous Fluids

288 FDA reports name Intravenous Fluids, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#431 of 2,679
by report volume (all drugs)
288
adverse-event reports
36.5%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Intravenous Fluids ranks #431 of 2679 by total reports (288) and #94 of 1130 by death-coded share (36.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#431
This drug, reports of 2679
#94
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Intravenous Fluids has 288 reports now versus 286 in that prior snapshot: 2 more (0.7%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Intravenous Fluids changes

Signature read: death-coded report count at 105 is the most distinctive stamp on Intravenous Fluids's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
288
Total Reports
105
Deaths Reported
36.5%
Death-coded share of reports

Active Ingredients

Intravenous Fluids

Administration Routes

IntravenousUnknown

Species Affected

Dog 209
Cat 76
Cougar 1
Lynx 1
Pig 1

Most Affected Breeds

Domestic Shorthair 49
Retriever - Labrador 24
Terrier - Bull - American Pit 12
Bulldog - French 11
Chihuahua 10
Retriever - Golden 10
Boxer (German Boxer) 9
Terrier - Yorkshire 8
Crossbred Canine/dog 8
Shih Tzu 8

Most Reported Reactions

Vomiting 83
Lethargy (see also Central nervous system depression in 'Neurological') 58
Death by euthanasia 57
Anorexia 57
Lethargy (see also Central nervous system depression in Neurological) 51
Death 48
Diarrhoea 47
Other abnormal test result NOS 38
Ataxia 37
Weight loss 33
Elevated blood urea nitrogen (BUN) 32
Fever 31

Outcome Breakdown

Ongoing
84 (29.2%)
Euthanized
57 (19.8%)
Recovered/Normal
54 (18.8%)
Died
48 (16.7%)
Outcome Unknown
44 (15.3%)
Recovered with Sequela
1 (0.3%)

Intravenous Fluids: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Intravenous Fluids, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (36.5% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Intravenous Fluids (#431 of 2,679 by report volume); death-coded 36.5%. PlainBreed drug row · death-coded report count stamp 105 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →