Drug profile

The FDA adverse-event record for Intranasal Vaccine For Brsv + Ibr + Pi3

11 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Intranasal Vaccine For Brsv + Ibr + Pi3. See the species affected, top reactions, and outcomes below.

11
adverse-event reports
63.6%
death-coded share
Cattle
most-reported species
7
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
7
Deaths Reported
63.6%
Death Rate

Active Ingredients

Intranasal Vaccine For Brsv + Ibr + Pi3

Administration Routes

NasalUnknownParenteral

Species Affected

Cattle 11

Most Affected Breeds

Crossbred Bovine/Cattle 4
Holstein-Friesian also known as Holstein 2
Charolais 1
Cattle (unknown) 1
Jersey 1
Mixed (Cattle) 1
Aberdeen Angus 1

Most Reported Reactions

Death 7
Anaphylaxis 3
Pulmonary disorder NOS 2
Pulmonary congestion 1
Abnormal necropsy finding 1
Lack of efficacy (bacteria) - NOS 1
Pulmonary oedema 1
Lung oedema 1
Respiratory tract disorder NOS 1
Injection site oedema 1
Diarrhoea 1
Decreased appetite 1

Outcome Breakdown

Died
7 (53.8%)
Outcome Unknown
4 (30.8%)
Recovered/Normal
2 (15.4%)

Intranasal Vaccine For Brsv + Ibr + Pi3 Adverse Event Insights

11 reports name Intranasal Vaccine For Brsv + Ibr + Pi3; 7 recorded a death outcome (63.6% of reported events, not a population-level mortality rate). Active ingredient: Intranasal Vaccine For Brsv + Ibr + Pi3. Administration routes: Nasal, Unknown, Parenteral.

By species: Cattle (11 reports). By breed: Crossbred Bovine/Cattle (4), Holstein-Friesian also known as Holstein (2), Charolais (1).

Leading clinical signs: Death (7), Anaphylaxis (3), Pulmonary disorder NOS (2), Pulmonary congestion (1). Outcome, 13 coded reports: Died leads at 53.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.