Drug profile

The FDA adverse-event record for Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus

485 FDA reports name Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#310 of 2,679
by report volume (all drugs)
485
adverse-event reports
90.9%
death-coded share
Cattle
most-reported species
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Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus ranks #310 of 2679 by total reports (485) and #6 of 1130 by death-coded share (90.9%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#310
This drug, reports of 2679
#6
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus has 485 reports now versus 479 in that prior snapshot: 6 more (1.3%).

Report change
+6
Death-coded reports
+6
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus changes

Signature read: Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus's 90.9% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
485
Total Reports
441
Deaths Reported
90.9%
Death-coded share of reports

Active Ingredients

Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus

Administration Routes

NasalSubcutaneousUnknownOralIntramuscular

Species Affected

Cattle 483
Unknown 1
Dog 1

Most Affected Breeds

Mixed (Cattle) 386
Aberdeen Angus 30
Holstein-Friesian also known as Holstein 24
Cattle (other) 20
Crossbred Bovine/Cattle 5
Red Angus 3
Jersey 3
Devon - South 2
Cattle (unknown) 2
Hereford cattle 2

Most Reported Reactions

Death 394
Lack of efficacy - NOS 324
Necropsy performed 63
Lack of efficacy (bacteria) - NOS 47
INEFFECTIVE, ANTIBIOTIC 30
Lack of efficacy (mycoplasma) - NOS 24
Unrelated death 19
Lack of efficacy (bacteria) - Mannheimia haemolytica 18
CULTURE/TITER DATA ABNORMAL 15
Lack of efficacy (bacteria) - Histophilus somni 14
Intentional misuse 14
Anaphylaxis 12

Outcome Breakdown

Died
432 (50.2%)
Outcome Unknown
276 (32.1%)
Recovered/Normal
62 (7.2%)
Ongoing
58 (6.7%)
Euthanized
17 (2.0%)
Recovered with Sequela
15 (1.7%)

Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (485 here).

Tilmicosin 486 Enalapril Maleate 487 Imidacloprid And Moxidectin 488 Ivermectin + Praziquantel 489

What to do with this drug

  • Compare Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Infectious Bovine Rhinotracheitis Virus(Ts), Rlb 106;Bovine Parainfluenza Virus (#310 of 2,679 by report volume); death-coded 90.9%. PlainBreed drug row · death-coded share stamp 90.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →