Drug profile

The FDA adverse-event record for Imidacloprid,Moxidectin

19 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Imidacloprid,Moxidectin. See the species affected, top reactions, and outcomes below.

19
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
8
Lack of efficacy (endoparasite) - heartworm - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
19
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Imidacloprid,Moxidectin

Administration Routes

TopicalUnknownOral

Species Affected

Dog 18
Cat 1

Most Affected Breeds

Dog (unknown) 3
Shepherd Dog - German 2
Newfoundland 2
Ridgeback - Rhodesian 2
Pit Bull 1
Catahoula Leopard Dog 1
Pointing Dog - German Short-haired 1
Pug 1
Coonhound - Treeing Walker 1
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1

Most Reported Reactions

Lack of efficacy (endoparasite) - heartworm 8
Lack of efficacy (endoparasite) - hookworm 4
Underdose 3
Lethargy (see also Central nervous system depression in Neurological) 3
Ear infection NOS 2
Vomiting 2
Itching 2
Foaming at the mouth 1
Vocalisation 1
Panting 1
Stomach upset 1
Elevated liver enzymes NOS 1

Outcome Breakdown

Outcome Unknown
12 (63.2%)
Ongoing
6 (31.6%)
Recovered/Normal
1 (5.3%)

Imidacloprid,Moxidectin Adverse Event Insights

19 reports name Imidacloprid,Moxidectin; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Imidacloprid,Moxidectin. Administration routes: Topical, Unknown, Oral.

By species: Dog (18 reports), Cat (1 reports). By breed: Dog (unknown) (3), Shepherd Dog - German (2), Newfoundland (2).

Leading clinical signs: Lack of efficacy (endoparasite) - heartworm (8), Lack of efficacy (endoparasite) - hookworm (4), Underdose (3), Lethargy (see also Central nervous system depression in Neurological) (3). Outcome, 19 coded reports: Outcome Unknown leads at 63.2%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.