Imidacloprid, Permethrin, Pyriproxyfen

28 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

0.0%

Death Rate

Active Ingredients

Imidacloprid, Permethrin, Pyriproxyfen

Administration Routes

Topical

Species Affected

Dog 28

Most Affected Breeds

Spitz - German Pomeranian 9

Retriever - Labrador 2

Mixed (Dog) 2

Shepherd Dog - German 2

Collie - Rough-haired 1

Shih Tzu 1

Akita 1

Plott 1

Pit Bull 1

Shepherd Dog (unspecified) 1

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 10

Decreased appetite 5

Lethargy (see also Central nervous system depression in 'Neurological') 4

Vomiting 3

Vocalisation 2

Diarrhoea 2

Behavioural disorder NOS 1

Ataxia 1

Fever 1

Musculoskeletal pain 1

Agitation 1

Localised pain NOS (see other 'SOCs' for specific pain) 1

Outcome Breakdown

Outcome Unknown

18 (64.3%)

Recovered/Normal

7 (25.0%)

Ongoing

3 (10.7%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.