Imidacloprid + Moxidectin
18,782 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
18,782
Total Reports
753
Deaths Reported
400.0%
Death Rate
Active Ingredients
ImidaclopridImidacloprid + MoxidectinMoxidectin
Administration Routes
TopicalUnknownOralOtherOphthalmicRespiratory (Inhalation)SubcutaneousTransdermalAuricular (Otic)Cutaneous
Species Affected
Dog 10,582
Cat 6,400
Unknown 1,347
Human 378
Rabbit 36
Ferret 19
Cockatiel 7
Wolf 6
Leopard 2
Mouse 2
Most Affected Breeds
Domestic Shorthair 3,794
Unknown 1,789
Retriever - Labrador 996
Cat (unknown) 927
Crossbred Canine/dog 680
Dog (unknown) 627
Chihuahua 603
Domestic Longhair 596
Terrier - Yorkshire 568
Shih Tzu 457
Most Reported Reactions
Lethargy (see also Central nervous system depression in 'Neurological') 2,397
Pruritus 2,282
Lack of efficacy (ectoparasite) - flea 2,253
Behavioural disorder NOS 1,768
Vomiting 1,503
Hypersalivation 1,096
Diarrhoea 1,027
Anorexia 986
Other abnormal test result NOS 964
Application site alopecia 900
Underfilling, Tubes 787
Ataxia 771
Outcome Breakdown
Outcome Unknown
9,187 (52.7%)
Recovered/Normal
6,881 (39.5%)
Ongoing
577 (3.3%)
Died
460 (2.6%)
Euthanized
293 (1.7%)
Recovered with Sequela
42 (0.2%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.