Drug profile

The FDA adverse-event record for Imidacloprid, Flumethrin

937 FDA reports name Imidacloprid, Flumethrin, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#193 of 2,679
by report volume (all drugs)
937
adverse-event reports
3.6%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Imidacloprid, Flumethrin ranks #193 of 2679 by total reports (937) and #873 of 1130 by death-coded share (3.6%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#193
This drug, reports of 2679
#873
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Imidacloprid, Flumethrin has 937 reports now versus 937 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Imidacloprid, Flumethrin changes

Signature read: 937 reports place Imidacloprid, Flumethrin in the upper third of FDA AER volume (#193 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
937
Total Reports
34
Deaths Reported
3.6%
Death-coded share of reports

Active Ingredients

Imidacloprid, Flumethrin

Administration Routes

TopicalUnknownCutaneousOralSubcutaneous

Species Affected

Dog 790
Cat 146
Unknown 1

Most Affected Breeds

Retriever - Labrador 74
Domestic Shorthair 69
Dog (unknown) 57
Retriever - Golden 45
Cat (unknown) 37
Shepherd Dog - Australian 36
Crossbred Canine/dog 35
Shih Tzu 33
Terrier - Yorkshire 31
Chihuahua 30

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 391
Lack of efficacy (ectoparasite) - tick NOS 92
Vomiting 75
Behavioural disorder NOS 66
Pruritus 58
Scratching 52
Other abnormal test result NOS 49
Seizure NOS 43
Lack of efficacy (bacteria) - Borrelia 40
Lethargy (see also Central nervous system depression in Neurological) 40
Diarrhoea 37
Lack of efficacy (endoparasite) - heartworm 33

Outcome Breakdown

Outcome Unknown
538 (57.5%)
Ongoing
241 (25.7%)
Recovered/Normal
119 (12.7%)
Died
22 (2.4%)
Euthanized
12 (1.3%)
Recovered with Sequela
4 (0.4%)

Imidacloprid, Flumethrin: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Imidacloprid, Flumethrin, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (3.6% here), distinct from the volume row.

What to do with this drug

  • Compare Imidacloprid, Flumethrin's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Imidacloprid, Flumethrin (#193 of 2,679 by report volume); death-coded 3.6%. PlainBreed drug row · report volume stamp 937 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →