Drug profile

The FDA adverse-event record for Imidacloprid And Moxidectin

488 FDA reports name Imidacloprid And Moxidectin, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#307 of 2,679
by report volume (all drugs)
488
adverse-event reports
2.5%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Imidacloprid And Moxidectin ranks #307 of 2679 by total reports (488) and #957 of 1130 by death-coded share (2.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#307
This drug, reports of 2679
#957
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Imidacloprid And Moxidectin has 488 reports now versus 488 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Imidacloprid And Moxidectin changes

Signature read: 488 reports place Imidacloprid And Moxidectin in the upper third of FDA AER volume (#307 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
488
Total Reports
12
Deaths Reported
2.5%
Death-coded share of reports

Active Ingredients

Imidacloprid And Moxidectin

Administration Routes

TopicalOralUnknownOtherOphthalmic

Species Affected

Dog 303
Cat 164
Human 14
Unknown 6
Rabbit 1

Most Affected Breeds

Domestic Shorthair 101
Mixed (Dog) 42
Unknown 21
Domestic Longhair 20
Terrier - Yorkshire 19
Retriever - Labrador 19
Dog (unknown) 18
Chihuahua 17
Cat (unknown) 17
Maltese 14

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 89
Pruritus 67
Vomiting 61
Behavioural disorder NOS 61
Ataxia 54
Other abnormal test result NOS 41
Hypersalivation 36
Diarrhoea 29
Muscle tremor 28
Application site alopecia 23
Inappetence 21
Anorexia 20

Outcome Breakdown

Outcome Unknown
242 (50.2%)
Recovered/Normal
220 (45.6%)
Died
8 (1.7%)
Ongoing
7 (1.5%)
Euthanized
4 (0.8%)
Recovered with Sequela
1 (0.2%)

Imidacloprid And Moxidectin: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Imidacloprid And Moxidectin, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (488 here).

What to do with this drug

  • Compare Imidacloprid And Moxidectin's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Imidacloprid And Moxidectin (#307 of 2,679 by report volume); death-coded 2.5%. PlainBreed drug row · report volume stamp 488 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →