Ibr / Pi3 (Orig S-P Us) Lv

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49 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
49
Total Reports
45
Deaths Reported
9180.0%
Death Rate

Active Ingredients

Ibr / Pi3 (Orig S-P Us) Lv

Administration Routes

NasalUnknownSubcutaneous

Species Affected

Cattle 49

Most Affected Breeds

Cattle (other) 23
Aberdeen Angus 11
Crossbred Bovine/Cattle 6
Charolais 2
Mixed (Cattle) 2
Red Angus 1
Holstein-Friesian also known as Holstein 1
Hereford cattle 1
Cattle (unknown) 1
Cattle (unspecified) 1

Most Reported Reactions

Death 42
Lack of efficacy - NOS 29
Respiratory signs 7
Lack of efficacy (bacteria) - NOS 7
Lameness 6
Death by euthanasia 5
INEFFECTIVE, ANTIBIOTIC 4
Lack of efficacy (endoparasite NOS) 4
Digestive tract disorder NOS 4
Other abnormal test result NOS 3
INEFFECTIVE, WEIGHT INC 3
Necropsy performed 3

Outcome Breakdown

Died
43 (38.1%)
Ongoing
28 (24.8%)
Recovered/Normal
20 (17.7%)
Outcome Unknown
14 (12.4%)
Euthanized
5 (4.4%)
Recovered with Sequela
3 (2.7%)

Data Summary

Metric Value
Total adverse event reports 49
Reports involving death 45
Case-fatality rate (reported events) 9180.0%
Distinct species in reports 1
Distinct breeds in reports 10
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Ibr / Pi3 (Orig S-P Us) Lv Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 49 adverse event reports referencing Ibr / Pi3 (Orig S-P Us) Lv, including 45 reports in which the animal died — a 9180.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Ibr / Pi3 (Orig S-P Us) Lv. Reported administration routes include Nasal, Unknown, Subcutaneous. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Ibr / Pi3 (Orig S-P Us) Lv reports are Cattle (49 reports), with Cattle accounting for the largest share. Within those species, Cattle (other) (23), Aberdeen Angus (11), Crossbred Bovine/Cattle (6) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Ibr / Pi3 (Orig S-P Us) Lv are Death (42), Lack of efficacy - NOS (29), Respiratory signs (7), Lack of efficacy (bacteria) - NOS (7). Of the 113 reports with a coded outcome, Died is the leading category at 38.1%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Ibr / Pi3 (Orig S-P Us) Lv.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial