Drug profile

The FDA adverse-event record for Hyaluronate

10 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Hyaluronate. See the species affected, top reactions, and outcomes below.

10
adverse-event reports
0.0%
death-coded share
Horse
most-reported species
3
Uncoded sign - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
10
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Hyaluronate

Administration Routes

UnknownOphthalmicIntra-ArticularSubcutaneousIntravenous

Species Affected

Horse 4
Unknown 4
Dog 2

Most Affected Breeds

Unknown 4
Thoroughbred 1
Rottweiler 1
Paint 1
Crossbred Equine/horse 1
Shepherd Dog - German 1
Quarter Horse 1

Most Reported Reactions

Uncoded sign 3
Solution, Abnormal 2
Diarrhoea 2
Anorexia 2
Nasal discharge 1
Excess tear flow 1
Restlessness 1
Vomiting 1
Depression 1
Blepharospasm 1
Epiphora 1
Conjunctivitis 1

Outcome Breakdown

Outcome Unknown
3 (50.0%)
Recovered/Normal
3 (50.0%)

Hyaluronate Adverse Event Insights

10 reports name Hyaluronate; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Hyaluronate. Administration routes: Unknown, Ophthalmic, Intra-Articular, Subcutaneous.

By species: Horse (4 reports), Unknown (4 reports), Dog (2 reports). By breed: Unknown (4), Thoroughbred (1), Rottweiler (1).

Leading clinical signs: Uncoded sign (3), Solution, Abnormal (2), Diarrhoea (2), Anorexia (2). Outcome, 6 coded reports: Outcome Unknown leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.