Drug profile

The FDA adverse-event record for Hexetidine

42 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Hexetidine. See the species affected, top reactions, and outcomes below.

42
adverse-event reports
2.4%
death-coded share
Dog
most-reported species
13
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
42
Total Reports
1
Deaths Reported
2.4%
Death Rate

Active Ingredients

Hexetidine

Administration Routes

OralPeriodontalUnknownOphthalmicTopical

Species Affected

Dog 35
Cat 5
Human 2

Most Affected Breeds

Crossbred Canine/dog 5
Dog (unknown) 4
Dachshund (unspecified) 4
Spitz - German Pomeranian 3
Domestic Shorthair 3
Chihuahua 2
Sheepdog - Shetland 2
Domestic (unspecified) 2
Maltese 2
Unknown 2

Most Reported Reactions

Vomiting 13
Lack of efficacy - NOS 6
Uncoded sign 5
Diarrhoea 3
Buccal irritation 2
Dysphagia 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Drooling 2
Tongue ulceration 1
Hypersalivation 1
Gingival disorder 1
Dyspnoea 1

Outcome Breakdown

Outcome Unknown
17 (56.7%)
Recovered/Normal
11 (36.7%)
Ongoing
1 (3.3%)
Euthanized
1 (3.3%)

Hexetidine Adverse Event Insights

42 reports name Hexetidine; 1 recorded a death outcome (2.4% of reported events, not a population-level mortality rate). Active ingredient: Hexetidine. Administration routes: Oral, Periodontal, Unknown, Ophthalmic.

By species: Dog (35 reports), Cat (5 reports), Human (2 reports). By breed: Crossbred Canine/dog (5), Dog (unknown) (4), Dachshund (unspecified) (4).

Leading clinical signs: Vomiting (13), Lack of efficacy - NOS (6), Uncoded sign (5), Diarrhoea (3). Outcome, 30 coded reports: Outcome Unknown leads at 56.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.