Drug profile

The FDA adverse-event record for Hetastarch

77 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Hetastarch. Species, reactions, and outcomes follow.

#893 of 2,679
by report volume (all drugs)
77
adverse-event reports
68.8%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Hetastarch ranks #892 of 2679 by total reports (77) and #34 of 1130 by death-coded share (68.8%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#892
This drug, reports of 2679
#34
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hetastarch has 77 reports now versus 77 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hetastarch changes

Signature read: Hetastarch's 68.8% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
77
Total Reports
53
Deaths Reported
68.8%
Death-coded share of reports

Active Ingredients

Hetastarch

Administration Routes

IntravenousUnknown

Species Affected

Dog 68
Cat 9

Most Affected Breeds

Retriever - Labrador 12
Domestic Shorthair 7
Chihuahua 4
Maltese 3
Schnauzer - Miniature 3
Collie - Border 3
Sheepdog - Shetland 3
Terrier - Yorkshire 3
Domestic Longhair 2
Boxer (German Boxer) 2

Most Reported Reactions

Vomiting 33
Other abnormal test result NOS 31
Death by euthanasia 29
Lethargy (see also Central nervous system depression in 'Neurological') 26
Death 25
Hypotension 24
Anorexia 22
Anaemia NOS 18
Elevated alanine aminotransferase (ALT) 18
Hypoalbuminaemia 17
Lateral recumbency 16
Elevated serum alkaline phosphatase (SAP) 15

Outcome Breakdown

Euthanized
28 (35.9%)
Died
25 (32.1%)
Ongoing
18 (23.1%)
Recovered/Normal
5 (6.4%)
Recovered with Sequela
1 (1.3%)
Outcome Unknown
1 (1.3%)

Hetastarch: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Hetastarch, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hetastarch (#893 of 2,679 by report volume); death-coded 68.8%. PlainBreed drug row · death-coded share stamp 68.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →